Effect of Huangqi Jianzhong Decoction Flavoring on Gastric Ulcer of Spleen and Stomach Deficiency Cold Type
Objective:To explore the effect of Huangqi Jianzhong Decoction Flavoring on gastric ulcer of spleen and stomach deficiency cold type.Method:A total of 76 patients with spleen and stomach deficiency cold type gastric ulcer treated in Zibo Traditional Chinese Medicine Hospital from June 2022 to August 2023 were selected.They were randomly divided into control group and observation group,38 cases in each group.The control group was given conventional treatment,and the observation group was given Huangqi Jianzhong Decoction Flavoring on the basis of control group.Inflammatory factors,traditional Chinese medicine symptom score,oxidative stress index before and after treatment and clinical efficacy of the two groups were compared.Result:After treatment,the levels of interleukin-10(IL-10),interleukin-6(IL-6)and tumor necrosis factor-α(TNF-α)in the two groups were lower than those before treatment,and the levels of IL-6,IL-10 and TNF-α in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).After treatment,malondialdehyde(MDA)in both groups was lower than that before treatment,superoxide dismutase(SOD)and glutathione peroxidase(GSH-Px)were higher than those before treatment,MDA in observation group was lower than that in control group,SOD and GSH-Px were higher than those in control group,the differences were statistically significant(P<0.05).After treatment,the scores of pain in the epigastric region,tightness in the chest and ribs,loss of appetite,belching,acid swallowing,and fatigue in both groups were lower than those before treatment,and the scores of pain in the epigastric region,tightness in the chest and ribs,loss of appetite,belching,acid swallowing,and fatigue in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).The total effective rate of the observation group was 94.74%,which was higher than 76.32%of the control group,and the difference was statistically significant(P<0.05).Conclusion:On the basis of western medicine treatment combined with Huangqi Jianzhong Decoction Flavoring can effectively reduce the inflammatory response of spleen and stomach deficiency cold type gastric ulcer patients,improve their oxidative stress response,improve their condition and improve the therapeutic effect.
Huangqi Jianzhong DecoctionSpleen stomach deficiency cold typeGastric ulcerInflammatory factorsOxidative stressTraditional Chinese medicine syndrome score
万方数据
维普
