Research Progress of Difficult-to-treat Rheumatoid Arthritis
Difficult-to-treat rheumatoid arthritis(D2T RA)is a complex subtype of rheumatoid arthritis(RA)characterized by limited or ineffective treatment with conventional disease-modifying antirheumatic drugs(DMARDs).This review of D2T RA aims to explore its clinical features and therapeutic strategies.The commonly used drug therapies include DMARDs,biologics and targeted therapeutic drugs.