Analgesic Effect and Safety of Ultrasound-guided Thoracic Paravertebral Nerve Block Combined with General Anesthesia in Radical Mastectomy
Objective:To analyze the analgesic effect and safety of ultrasound-guided thoracic paravertebral nerve block combined with general anesthesia in radical mastectomy.Method:A total of 120 patients with radical mastectomy treated in Qingliu County General Hospital from February 2022 to July 2023 were selected.According to random number table method,they were divided into conventional anesthesia group and combined anesthesia group,60 cases in each group.The conventional anesthesia group received general anesthesia,and the combined anesthesia group received ultrasound-guided thoracic paravertebral nerve block combined with general anesthesia.The pain degree at 2 h,4 h,8 h and 12 h after surgery,cognitive function before and 3 d after surgery,anesthetic drug dosage and adverse reactions were compared between the two groups.Result:The visual analogue scale(VAS)scores in the combined anesthesia group were lower than those in the conventional anesthesia group at 2 h,4 h,8 h and 12 h after surgery,and the differences were statistically significant(P<0.05).The score of mini cognitive mental state assessment scale(MMSE)in the combined anesthesia group was higher than that in the conventional anesthesia group,and the dosage of Propofol was significantly lower than that in the conventional anesthesia group,the differences were statistically significant(P<0.05).The incidence of adverse reactions in combined anesthesia group was lower than that in conventional anesthesia group,and the difference was statistically significant(P<0.05).Conclusion:Ultrasound-guided thoracic paravertebral nerve block combined with general anesthesia for patients undergoing radical mastectomy can effectively improve the degree of postoperative pain,reduce the incidence of adverse reactions,and have little impact on the cognitive degree of patients,with ideal effects.
万方数据
维普
