Effect of Banxia Baizhu Tianma Decoction in the Adjuvant Treatment of Acute Cerebral Infarction with Wind-phlegm-blocked Collaterals Syndrome
Objective:To investigate the effect of Banxia Baizhu Tianma Decoction in the adjuvant treatment of acute cerebral infarction(ACI)with wind-phlegm-blocked collaterals syndrome.Method:A total of 94 ACI patients with wind-phlegm-blocked collaterals syndrome who admitted to Chuzhou Hospital of Traditional Chinese Medicine in Huai'an City from November 2021 to May 2023 were selected as the study objects,the patients were randomly divided into the conventional group and the treatment group,with 47 cases in each group.The conventional group was treated with conventional western medicine,and the treatment group was treated with Banxia Baizhu Tianma Decoction on the basis of this,two groups were treated for 14 d.The clinical efficacy,neurological function,inflammatory factor levels and oxidative stress response were compared between two groups.Result:The total effective rate of the treatment group was 95.74%,which was higher than 80.85%of the conventional group,the difference was statistically significant(P<0.05).After treatment,the National Institute of Health stroke scale(NIHSS)scores of two groups were decreased compared with those before treatment,and that in the treatment group was lower than that of the conventional group,the differences were statistically significant(P<0.05).After treatment,the matrix metalloproteinase-9(MMP-9),tumor necrosis factor-α(TNF-α)and interleukin-8(IL-8)in two groups were decreased compared with those before treatment,and which in the treatment group were lower than those in the conventional group,the differences were statistically significant(P<0.05).After treatment,the malondialdehyde(MDA)in two groups were lower than those before treatment,and the SOD were higher than those before treatment,and the MDA in the treatment group was lower than that in the conventional group,and the SOD was higher than that in the conventional group,the differences were statistically significant(P<0.05).Conclusion:Banxia Baizhu Tianma Decoction is effective in the adjuvant treatment of ACI with wind-phlegm-blocked collaterals syndrome,which can reduce the expression of inflammatory factor,reduce oxidative stress response and improve neurological function.
Acute cerebral infarctionWind-phlegm-blocked collaterals syndromeBanxia Baizhu Tianma DecoctionNeural function
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