Analysis of Risk Factors for Multidrug-resistant Bacterial Infections in Surgical Patients in Specialized Cancer Hospital
Objective:To analyze the risk factors of multi-drug resistant organism(MDRO)infection in surgical patients in cancer hospitals,targeted preventive measures were taken to reduce the MDRO infection rate in surgical patients.Method:Using the method of retrospective investigation,the data of 117,841 patients who underwent surgery in Harbin Medical University Cancer Hospital from January 1,2019 to December 31,2022 were collected from the hospital infection database,and the diagnosis was made according to the Hospital Infection Diagnostic Criteria.The basic information,pathogen detection and composition ratio of patients with MDRO infection were compared between two groups,and the influencing factors of MDRO infection were analyzed by multivariate logistic regression.Result:There were significant differences in age,length of operation,length of hospitalization,length of catheter use,length of central venous catheter use,male,use of catheter,use of central venous catheter,transfer to ICU,blood transfusion and secondary operation between two groups(P<0.05).A total of 277 strains of multidrug-resistant bacteria were detected in patients with MDRO infection,among them,G-bacilli accounted for 61.7%,and G+cocci accounted for 38.3%,among them,Escherichia coli was the main,followed by Baumanii/Acinetobacter calcoaceticus complex and Staphylococcus epidermidis,the submitted specimens were mainly sputum specimens(38.5%).Multivariate logistic regression analysis showed that age,length of hospital stay,length of surgery,use of central venous catheter,and transfer to ICU were independent risk factors for MDRO(P<0.05).Conclusion:The older the age,the longer the operation time and hospitalization time,the use of central venous catheter and the transfer to ICU will increase the risk of MDRO infection in surgical patients.
万方数据
维普
