Research Progress on Correlation between Atherogenic Index of Plasma and Total Load of Cerebral Small Vessel Disease
Cerebral small vessel disease(CSVD)is a group of diseases with similar clinical symptoms and imaging findings caused by different etiologies,which mainly affects the higher vascular network such as small arteries and small veins in the brain.At present,the pathophysiological mechanism of CSVD is still not completely clear,but atherosclerosis(AS)is one of the main pathological mechanisms of cerebral vascular diseases,and lipids play a very important role in the pathogenesis of AS.With the in-depth study of a large number of scholars,it is believed that the atherogenic index of plasma(AIP)and its related traditional lipid indexes are closely related to CSVD.Starting from the occurrence and development of AIP and CSVD,this study deeply discussed the correlation between AIP and relevant traditional lipid indexes and CSVD types,integrated the total imaging load of CSVD to reflect the severity of CSVD,and further explored the correlation between AIP and traditional lipid indexes and total CSVD load.Finally,the correlation between AIP and CSVD severity was determined.This paper reviews the research progress of correlation between AIP and its related traditional indicators and total load of CSVD,and comprehensively expounds the influence of lipid on total load of CSVD,which provides a new basis for establishing comprehensive evaluation indicators of total load of CSVD in clinic.
Atherogenic Index of plasmaCerebral small vessel diseaseTotal load of cerebral small vessel diseaseBlood lipidsReview
万方数据
维普
