Coronary atherosclerotic heart disease(CHD),referred to as coronary heart disease for short,is a cardiovascular disease with a high incidence in the world,percutaneous coronary intervention(PCI)is an effective treatment for CHD at present,but in-stent restenosis(ISR)affects the prognosis of patients and increases the risk of cardiovascular events.With the application of bare-metal stent(BMS),the treatment of ISR patients has entered a new stage,after that,drug-coated stents(DES),drug-coated balloon(DCB),plaque ablation technology and degradable materials are gradually applied,which provides more choices for disease treatment,and it is more conducive to improving the treatment effect.Based on this,this article provided a review of the concept,pathogenesis and treatment progress of ISR.
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