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PCI术后支架内再狭窄的治疗进展

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冠状动脉粥样硬化性心脏病(coronary atherosclerotic heart disease,CHD)简称冠心病,是全世界发生率较高的心血管疾病,经皮冠状动脉介入(percutaneous coronary intervention,PCI)是现阶段CHD治疗的有效方法,但支架内再狭窄(in-stent restenosis,ISR)影响着患者预后,增加不良心血管事件发生风险。随着裸金属支架(bare-metal stent,BMS)的应用,ISR患者的治疗进入一个新阶段,之后药物涂层支架(drug eluting stents,DES)、药物涂层球囊(drug-coated balloon,DCB)、斑块消融技术及可降解材料逐渐应用,为疾病治疗提供更多的选择,更有利于提高治疗效果。基于此,本文通过对ISR概念、发生机制、治疗进展进行综述。
Progress in the Treatment of In-stent Restenosis after PCI
Coronary atherosclerotic heart disease(CHD),referred to as coronary heart disease for short,is a cardiovascular disease with a high incidence in the world,percutaneous coronary intervention(PCI)is an effective treatment for CHD at present,but in-stent restenosis(ISR)affects the prognosis of patients and increases the risk of cardiovascular events.With the application of bare-metal stent(BMS),the treatment of ISR patients has entered a new stage,after that,drug-coated stents(DES),drug-coated balloon(DCB),plaque ablation technology and degradable materials are gradually applied,which provides more choices for disease treatment,and it is more conducive to improving the treatment effect.Based on this,this article provided a review of the concept,pathogenesis and treatment progress of ISR.

Coronary atherosclerotic heart diseasePercutaneous coronary interventionIn-stent restenosisTreatment progress

余一平

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绍兴文理学院医学院 浙江 绍兴 312000

冠状动脉粥样硬化性心脏病 经皮冠状动脉介入 支架内再狭窄 治疗进展

2024

中外医学研究
中国医院管理杂志社

中外医学研究

影响因子:1.149
ISSN:1674-6805
年,卷(期):2024.22(14)
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