Clinical Effect of Tirofiban Hydrochloride Assisted PCI in the Treatment of Acute Myocardial Infarction
Objective:To investigate the clinical effect of Tirofiban Hydrochloride assisted percutaneous coronary intervention(PCI)in the treatment of acute myocardial infarction(AMI).Method:A total of 100 AMI patients who admitted to Yanbian University Hospital(Yanbian Hospital)from August 2021 to June 2023 were selected as the study objects,and they were randomly divided into the control group(50 cases)and the observation group(50 cases)according to the random number table method.The control group was given PCI treatment,while the observation group was given Tirofiban Hydrochloride assisted PCI treatment.The clinical efficacy,cardiac function,myocardial injury markers,inflammatory factors and adverse reactions between two groups were compared.Result:The total clinical effective rate of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).Before treatment,there were no significant differences in the levels of cardiac function,myocardial injury markers and inflammatory factors between two groups(P>0.05);after treatment,the left ventricular ejection fraction(LVEF)in two groups were increased compared with those before treatment,and that in the observation group was higher than that in the control group,the left ventricular end systolic diameter(LVESD),left ventricular end diastolic diameter(LVEDD),levels of serum troponin I(cTnI),creatine kinase isoenzyme(CK-MB),interleukin-6(IL-6)and hypersensitive C-reactive protein(hs-CRP)in two groups were decreased compared with those before treatment,and those in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between two groups(P>0.05).Conclusion:Tirofiban Hydrochloride assisted PCI treatment is more effective in the treatment of AMI patients,which can effectively improve cardiac function,reduce myocardial injury,reduce inflammatory reactions,and it is safe and reliable.
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