中外医学研究2024,Vol.22Issue(15) :179-184.DOI:10.14033/j.cnki.cfmr.2024.15.045

非酒精性脂肪性肝病的研究进展

Research Progress of Non-alcoholic Fatty Liver Disease

聂静 唐映梅 郭玲 程思根 罗志刚 张虹雨
中外医学研究2024,Vol.22Issue(15) :179-184.DOI:10.14033/j.cnki.cfmr.2024.15.045

非酒精性脂肪性肝病的研究进展

Research Progress of Non-alcoholic Fatty Liver Disease

聂静 1唐映梅 2郭玲 1程思根 1罗志刚 1张虹雨1
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作者信息

  • 1. 昆明市第一人民医院 云南 昆明 650100
  • 2. 昆明医科大学第二附属医院
  • 折叠

摘要

非酒精性脂肪性肝病(non-alcoholic fatty liver disease,NAFLD)是一种与胰岛素抵抗和代谢综合征相关的慢性肝脏疾病.随着全球肥胖和糖尿病患者的增加,NAFLD的发病率也在逐年上升,成为全球范围内一个重要的公共卫生问题.NAFLD患者常会出现乏力、腹胀、右上腹不适或疼痛等症状,严重时可出现肝硬化、肝细胞癌等,这时会出现呕血、黑便、血便等症状,对患者的身体健康和生命质量产生严重的影响.因此,及时的诊断和治疗对改善NAFLD患者预后至关重要.本文将从NAFLD的发病机制、病理生理、流行病学特点、临床表现、诊断和治疗等方面进行综述.

Abstract

Non-alcoholic fatty liver disease(NAFLD)is a chronic liver disease associated with insulin resistance and the metabolic syndrome.With the increase of obesity and diabetes patients worldwide,the incidence of NAFLD is also increasing year by year,becoming an important public health problem worldwide.NAFLD patients often have fatigue,abdominal distension,right upper abdomen discomfort or pain and other symptoms,in severe cases,liver cirrhosis,hepatocellular carcinoma can appear,at this time,there will be hematemesis,black stool,blood stool and other symptoms,which will have a serious impact on the patients'health and quality of life.Therefore,prompt diagnosis and treatment are essential to improve the prognosis of patients with NAFLD.This review will review the pathogenesis,pathophysiology,epidemiological characteristics,clinical manifestations,diagnosis and treatment of NAFLD.

关键词

非酒精性脂肪性肝病/发病机制/流行病学/临床表现/诊断和治疗

Key words

Non-alcoholic fatty liver disease/Pathogenesis/Epidemiology/Clinical manifestations/Diagnosis and treatment

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基金项目

昆明市卫生科技人才培养项目暨"十百千"工程培养计划(2021-sw后备-17)

出版年

2024
中外医学研究
中国医院管理杂志社

中外医学研究

影响因子:1.149
ISSN:1674-6805
参考文献量4
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