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三维能量多普勒血流定量技术联合常规超声对早期乳腺癌诊断价值

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目的:探讨三维能量多普勒血流定量技术联合常规超声对早期乳腺癌诊断价值。方法:回顾性选取 2020 年12 月—2022 年 10 月仙桃市第四人民医院收治的 50 例早期乳腺癌患者作为早期乳腺癌组,30 例癌前病变患者作为癌前病变组,另选取同期体检 30 例乳腺良性肿瘤患者作为良性组。三组均进行常规超声及三维能量多普勒血流定量技术检测。比较三组三维能量多普勒超声图像特征。比较三组三维能量多普勒超声血流定量参数。以病理穿刺活检为金标准,分析三维能量多普勒血流定量技术、常规超声单独检测与联合检测对早期乳腺癌的诊断价值。结果:早期乳腺癌组后方回声衰减、纵横比<1、有微钙化、边界不清晰、病灶形态不规则及血流分级 2 级、3 级所占比例高于良性组和癌前病变组,差异有统计学意义(P<0。05)。早期乳腺癌组血管形成指数(vascularization index,VI)、血流指数(flow index,FI)、血管形成-血流指数(vascularity flow index,VFI)、彩色像素密度(color pixel density,CPD)均高于癌前病变组和良性组,癌前病变组VI、FI、VFI、CPD均高于良性组,差异有统计学意义(P<0。05)。联合检测的敏感度、准确度、阴性预测值均高于常规超声,差异有统计学意义(P<0。05)。常规超声与病理诊断的一致性一般(Kappa=0。526,P<0。05),三维能量多普勒血流定量技术、联合检测与病理诊断具有较高的一致性(Kappa=0。812、0。919,P<0。05)。结论:不同程度乳腺肿块患者其三维能量多普勒超声图像存在差异,三维能量多普勒血流定量技术联合常规超声具有较高的诊断价值。
Value of Three-dimensional Energy Doppler Blood Flow Quantification Technology Combined with Conventional Ultrasound in the Diagnosis of Early Breast Cancer
Objective:To explore the value of three-dimensional energy Doppler blood flow quantification technology combined with conventional ultrasound in the diagnosis of early breast cancer.Method:Fifty patients with early breast cancer admitted to the Fourth People's Hospital of Xiantao City from December 2020 to October 2022 were retrospectively selected as the early breast cancer group,30 patients with precancerous lesions were selected as the precancerous lesion group,and 30 patients with benign breast tumors who underwent physical examination during the same period were selected as the benign group.The three groups were tested by conventional ultrasound and three-dimensional energy Doppler blood flow quantitative technique.The characteristics of three-dimensional energy Doppler ultrasound images were compared among the three groups.The blood flow quantitative parameters of three-dimensional energy Doppler ultrasound were compared among the three groups.Taking pathological puncture biopsy as the gold standard,the diagnostic value of three-dimensional energy Doppler blood flow quantification technique,conventional ultrasound detection alone and combined detection in early breast cancer was analyzed.Result:The proportions of rear echo attenuation,aspect ratio<1,microcalcification,unclear boundary,irregular lesion shape and blood flow grade 2 and 3 in early breast cancer group were higher than those in benign group and precancerous lesion group,and the differences were statistically significant(P<0.05).Vascularization index(VI),flow index(FI),vascularity flow index(VFI)and color pixel density(CPD)were higher than those in precancerous lesion group and benign group,and VI,FI,VFI and CPD in precancerous lesion group were higher than those in benign group,and the differences were statistically significant(P<0.05).The sensitivity,accuracy and negative predictive value of combined detection were higher than those of conventional ultrasound,and the differences were statistically significant(P<0.05).Conventional ultrasound was generally consistent with pathological diagnosis(Kappa=0.526,P<0.05),while three-dimensional energy Doppler blood flow quantitative technology and combined detection were highly consistent with pathological diagnosis(Kappa=0.812,0.919,P<0.05).Conclusion:The three-dimensional energy Doppler ultrasound images of patients with different degrees of breast mass are different,and the three-dimensional energy Doppler blood flow quantitative technique combined with conventional ultrasound has high diagnostic value.

Three-dimensional energy Doppler blood flow quantification techniqueConventional ultrasoundEarly breast cancerDiagnostic value

武丽娜、阎华

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仙桃市第四人民医院 湖北 仙桃 433000

荆州市第三人民医院

三维能量多普勒血流定量技术 常规超声 早期乳腺癌 诊断价值

2024

中外医学研究
中国医院管理杂志社

中外医学研究

影响因子:1.149
ISSN:1674-6805
年,卷(期):2024.22(16)