Effects of Metaraminol Combined with Combined Spinal Epidural Anesthesia on Parturients Undergoing Cesarean Section
Objective:To explore the effects of Metaraminol combined with combined spinal epidural anesthesia on parturients undergoing cesarean section.Method:A total of 100 parturients waiting for cesarean section in Quanzhou First Hospital from January 2021 to October 2022 were selected.According to random number method,the patients were divided into combined spinal epidural anesthesia group and combined treatment group,50 cases in each group.The combined spinal epidural anesthesia group was given combined spinal epidural anesthesia,and the combined treatment group was given Metaraminol combined with combined combined spinal epidural anesthesia.Systolic blood pressure(SBP),diastolic blood pressure(DBP),mean arterial pressure(MAP),cardiac output(CO),heart rate(HR),cardiac index(CI)before anesthesia and after surgery,surgical indexes,neonatal hypoxia condition and adverse reactions were compared between the two groups.Result:After surgery,DBP,SBP and MAP were decreased in two groups,but DBP,SBP and MAP in the combined treatment group were higher than those in the combined spinal epidural anesthesia group,the differences were statistically significant(P<0.05).After surgery,HR,CO and CI were decreased in two groups,but HR,CO and CI in the combined treatment group were higher than those in the combined spinal epidural anesthesia group group,the differences were statistically significant(P<0.05).There were no significant differences in the surgery time,intraoperative blood loss volume and intraoperative fluid infusion volume between two groups(P>0.05).There were no significant differences in Apgar scores at 1 min and 5 min between two groups(P>0.05).The incidence of adverse reactions in the combined treatment group was lower than that in the combined spinal epidural anesthesia group,and the difference was statistically significant(P<0.05).Conclusion:The intervention of Metaraminol combined with combined spinal epidural anesthesia parturients undergoing cesarean section can better maintain the level of blood pressure and heart rate,regulate the blood flow dynamics,and have a small effect on neonatal Apgar score,with significant effect.