首页|翼状胬肉切除与角膜缘干细胞移植联合治疗对翼状胬肉患者角膜散光及视力的影响

翼状胬肉切除与角膜缘干细胞移植联合治疗对翼状胬肉患者角膜散光及视力的影响

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目的:探究翼状胬肉切除联合角膜缘干细胞移植对翼状胬肉患者的影响.方法:选取2020年3月—2023年3月镇江市第四人民医院收治的100例翼状胬肉患者作为研究对象,按随机数表法分为两组,各50例.对照组行翼状胬肉切除治疗,观察组在对照组基础上加用角膜缘干细胞移植治疗.比较两组临床疗效、拆线时间、角膜上皮修复时间、视力恢复情况、泪膜功能及并发症发生情况.结果:观察组治疗总有效率高于对照组,拆线时间、角膜上皮修复时间早于对照组,并发症总发生率低于对照组,差异有统计学意义(P<0.05).术后3个月,观察组最佳矫正视力(BCVA)、角膜水平曲度、角膜垂直曲度高于对照组,角膜散光度低于对照组,泪膜破裂时间(BUT)、泪液分泌试验(SⅠT)长于对照组,差异有统计学意义(P<0.05).结论:翼状胬肉切除联合角膜缘干细胞移植可修复翼状胬肉患者角膜上皮,改善视力,有利于泪膜功能的提升,且并发症少.
Effects of Pterygium Excision Combined with Limbal Stem Cell Transplantation on Corneal Astigmatism and Visual Acuity in Patients with Pterygium
Objective:To explore the effect of pterygium excision combined with limbal stem cell transplantation on pterygium patients.Method:A total of 100 patients with pterygium treated in Zhenjiang Fourth People's Hospital from March 2020 to March 2023 were selected as the study objects,and divided into two groups according to random number table method,with 50 cases in each group.The control group was treated with pterygium excision,the observation group treated with limbal stem cell transplantation on the basis of the control group.The clinical effect,removal time,repair time of corneal epithelium,vision recovery,tear film function and complications were compared between the two groups.Result:The total effective rate of the observation group was higher than that of the control group,the time of suture removal and corneal epithelial repair were earlier than those of the control group,and the total incidence of complications was lower than that of the control group,the differences were statistically significant(P<0.05).At 3 months after surgery,the best corrected visual acuity(BCVA),horizontal curvature of cornea and vertical curvature of cornea in observation group were higher than those in control group,corneal astigmatism was lower than that in control group,tear film rupture time(BUT)and tear secretion test(SⅠT)were longer than those in control group,the differences were statistically significant(P<0.05).Conclusion:Pterygium excision and limbal stem cell transplantation can repair the corneal epithelium of pterygium patients,improve visual acuity,and promote tear film function with few complications.

PterygiumExcision of pterygiumCorneal limbal stem cell transplantationComplications

郭伟、徐恒

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镇江市第四人民医院 江苏 镇江 212000

翼状胬肉 翼状胬肉切除 角膜缘干细胞移植 并发症

2024

中外医学研究
中国医院管理杂志社

中外医学研究

影响因子:1.149
ISSN:1674-6805
年,卷(期):2024.22(19)