Effects of Jianpi Huashi Decoction on Clinical Symptoms,Pathological Degree of Gastric Mucosa and Gastric Function Indexes of Chronic Atrophic Gastritis
Objective:To investigate the effects of Jianpi Huashi Decoction on clinical symptoms,pathological degree of gastric mucosa and gastric function indexes in patients with chronic atrophic gastritis.Method:A total of 86 patients with chronic atrophic gastritis admitted to the Internal Digestive System Department of Zhejiang Provincial Hospital of Traditional Chinese Medicine from September 2022 to May 2023 were selected as the study objects and divided into two groups according to random number table method,with 43 cases in each group.The control group was treated with conventional western medicine,and the observation group was treated with Jianpi Huashi Decoction at the same time.The clinical symptoms,total effective rate,pathological degree of gastric mucosa and gastric function indexes were compared between the two groups.Result:The total effective rate of the observation group was 95.35%,which was higher than 79.07%of the control group,the difference was statistically significant(P<0.05).After treatment,the scores of epigastric pain,epigastric fullness,hypoglycemia and epigastric burning in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).After treatment,the scores of intrinsic glands,intestinal metaplasia and dysplasia in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).After treatment,the levels of serum pepsin Ⅰ(PGⅠ)and gastrin-17(G-17)in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).Conclusion:The application of Jianpi Huashi Decoction in the treatment of chronic atrophic gastritis can further improve the clinical effect,promote the effective relief of clinical symptoms,and improve the pathological degree of gastric mucosa and gastric function.
Jianpi Huashi DecoctionChronic atrophic gastritisClinical symptomsGastric mucosa pathologyGastric function