首页|胸部LDCT人工智能联合医师诊断在肺结节良恶性鉴别中的应用价值

胸部LDCT人工智能联合医师诊断在肺结节良恶性鉴别中的应用价值

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目的:探讨胸部低剂量CT(LDCT)人工智能联合医师诊断在肺结节良恶性鉴别中的应用价值。方法:回顾性分析 2022 年 1 月—2023 年 9 月惠州市第三人民医院收治的 225 例肺结节患者临床资料。所有患者均行胸部LDCT扫描。分析金标准、胸部LDCT医师诊断、胸部LDCT人工智能联合医师诊断良恶性肺结节检出情况。比较胸部LDCT医师诊断、胸部LDCT人工智能联合医师诊断的诊断价值。分析胸部LDCT医师诊断、胸部LDCT人工智能联合医师诊断与金标准的一致性。比较良恶性肺结节胸部LDCT影像学特征。分析不同成分肺结节胸部LDCT人工智能联合医师诊断恶性结节准确性。结果:225 例患者经金标准检出 139 例恶性。胸部LDCT医师诊断检出 134 例恶性,占比为 96。40%(134/139);胸部LDCT人工智能联合医师诊断检出 138 例恶性,占比为 99。28%(138/139)。Kappa检验显示,胸部LDCT医师诊断、胸部LDCT人工智能联合医师诊断与金标准的Kappa值分别为 0。860、0。972(P<0。001)。胸部LDCT人工智能联合医师诊断敏感度、准确度、阴性预测值均高于胸部LDCT医师诊断,差异有统计学意义(P<0。05)。恶性肺结节患者短毛刺征、胸膜凹陷征、血管集束征、分叶征、空泡征占比均高于良性肺结节患者,差异有统计学意义(P<0。05)。225 例患者中,实性结节 117 例,恶性结节 54 例;部分实性结节 60 例,恶性结节 49 例;纯磨玻璃结节 48 例,恶性结节 36 例。胸部LDCT人工智能联合医师诊断实性结节恶性准确率为 98。15%(53/54);部分实性结节恶性准确率为 100。00%(49/49);纯磨玻璃结节恶性诊断准确率为97。22(35/36)。结论:胸部LDCT人工智能联合医师诊断可提高肺结节良恶性鉴别诊断价值,可据此早期制定精准治疗方案,以改善患者预后。
Application Value of Thoracic LDCT Artificial Intelligence Combined with Physician Diagnosis in Identify of Benign and Malignant Pulmonary Nodules
Objective:To explore the application value of thoracic low dose CT(LDCT)artificial intelligence combined with physician diagnosis in identify of benign and malignant pulmonary nodules.Method:A total of 225 patients with pulmonary nodules admitted to the Huizhou Third People's Hospital from January 2022 to September 2023 were selected.Thoracic LDCT scan was performed in all patients.The benign and malignant pulmonary nodules detection condition of gold standard,thoracic LDCT physician diagnosis,thoracic LDCT artificial intelligence combined with physician diagnosis was analyzed.The diagnostic value of thoracic LDCT physicians diagnosis and thoracic LDCT artificial intelligence combined with physicians diagnosis was compared.The consistency of thoracic LDCT physician diagnosis,thoracic LDCT artificial intelligence combined physician diagnosis and gold standard was analyzed.The thoracic LDCT imaging features of benign and malignant pulmonary nodules were compared.The malignant diagnosis accuracy of different components of pulmonary nodules thoracic LDCT artificial intelligence combined with physicians diagnose was analyzed.Result:Among 225 patients,139 malignant cases detected by gold standard.There were 134 malignant cases detected by LDCT physicians diagnosis,accounting for 96.40%(134/139).Thoracic LDCT artificial intelligence combined with physicians diagnosis detected 138 malignant cases,accounting for 99.28%(138/139).The Kappa test showed that the Kappa values of the thoracic LDCT physician diagnosis,thoracic LDCT artificial intelligence combined physician diagnosis and gold standard were 0.860 and 0.972 respectively(P<0.001).The sensitivity,accuracy and negative predictive value of thoracic LDCT artificial intelligence combined with physicians diagnosis were higher than those of thoracic LDCT physicians diagnosis,and the differences were statistically significant(P<0.05).The proportions of short burr sign,pleural depression sign,vascular cluster sign,lobular sign and vacuole sign in patients with malignant pulmonary nodules were higher than those in patients with benign pulmonary nodules,and the differences were statistically significant(P<0.05).Among the 225 patients,117 cases were solid nodules and 54 cases were malignant nodules.There were 60 cases of partial solid nodules and 49 cases of malignant nodules.There were 48 cases of pure glass nodules and 36 cases of malignant nodules.The accuracy rate of malignant in solid nodules by thoracic LDCT artificial intelligence combined with physicians diagnosis was 98.15%(53/54),the malignant accuracy of partial solid nodules was 100.00%(49/49),the accuracy of malignant diagnosis of pure ground glass nodules was 97.22%(35/36).Conclusion:Thoracic LDCT artificial intelligence combined with physicians diagnosis can improve the value of differential diagnosis of benign and malignant pulmonary nodules,which can contribute to the early formulation of accurate treatment plan and improve patient prognosis.

Pulmonary nodulesArtificial intelligenceThoracic low dose CTDifferential diagnosis

杨玉丽、石先琼、柯双好、周睿

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惠州市第三人民医院 广东 惠州 516000

肺结节 人工智能 胸部低剂量CT 鉴别诊断

惠州市科技计划项目

221014156941115

2024

中外医学研究
中国医院管理杂志社

中外医学研究

影响因子:1.149
ISSN:1674-6805
年,卷(期):2024.22(20)