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乳腺叶状肿瘤与乳腺纤维腺瘤的MRI鉴别诊断价值

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目的:探讨乳腺叶状肿瘤(PTB)与乳腺纤维腺瘤的磁共振成像(MRI)鉴别诊断价值。方法:选取 2021 年5 月—2023 年 5 月六盘水市人民医院收治的 45 例PTB及 45 例乳腺纤维腺瘤患者作为研究对象,均行MRI检查,统计MRI检出PTB与乳腺纤维腺瘤情况,并以手术结果为金标准,分析MRI鉴别诊断PTB与乳腺纤维腺瘤的效能;采用Kappa检验验证MRI诊断与手术结果的一致性;比较PTB与乳腺纤维腺瘤在瘤体形态、瘤体大小、增强后边界形态、囊变、低信号分隔、时间-信号强度曲线(TIC)类型、瘤周晕征、T2WI抑脂信号、表观扩散系数(ADC)值、T1WI高信号等方面的差异性。结果:90 例患者中经MRI检出PTB 44 例,乳腺纤维腺瘤 46 例;MRI鉴别诊断PTB与乳腺纤维腺瘤的敏感度为 97。78%、特异度为 100。00%,准确度为 98。89%,阳性预测值为 100。00%,阴性预测值为 97。83%;采用Kappa检验显示,MRI与金标准一致性极好(Kappa=0。978,P<0。001);两组瘤体形态、瘤体大小、囊变、瘤周晕征、T2WI抑脂信号、T1WI高信号比较,差异有统计学意义(P<0。05)。结论:MRI在PTB与乳腺纤维腺瘤鉴别诊断中具有较高价值,可提高诊断准确性,便于后续针对性治疗方案制定。
MRI for Differential Diagnosis of Phyllode Tumor of the Breast and Breast Fibroadenoma
Objective:To investigate the differential diagnostic value of phyllode tumor of the breast(PTB)and breast fibroadenoma.Method:A total of 45 patients with PTB and 45 patients with breast fibroadenoma treated in Liupanshui People's Hospital from May 2021 to May 2023 were selected as the study objects.All patients underwent MRI examination,and statistical MRI detection of PTB and breast fibroadenoma was performed,and the surgical results were used as the gold standard to analyze the efficacy of MRI in the differential diagnosis of PTB and breast fibroadenoma.Kappa test was used to verify the consistency of MRI diagnosis and surgical results.The differences between PTB and breast fibroadenoma were compared in tumor shape,tumor size,enhanced boundary shape,cystic degeneration,low signal separation,type of time-signal intensity curve(TIC),peri-tumor halo sign,T2WI fat suppression signal,apparent diffusion coefficient(ADC)value,and T1WI high signal.Result:Among the 90 patients,a total of 44 cases of PTB and 46 cases of breast fibroadenoma were detected by MRI.The sensitivity,specificity,accuracy,positive predictive value,and negative predictive value of MRI were 97.78%,100.00%,100.00%,and 97.83%respectively in the differential diagnosis of PTB and breast fibroadenoma.Kappa test showed that MRI was in good agreement with gold standard(Kappa=0.978,P<0.001).There were significant differences in tumor morphology,tumor size,cystic change,peritumoral halo sign,fat suppression signal on T2WI and high signal on T1WI between the two groups(P<0.05).Conclusion:MRI has a high value in the differential diagnosis of PTB and breast fibroadenoma,which can improve the diagnostic accuracy and facilitate the formulation of subsequent targeted treatment plans.

Phyllodes tumor of the breastBreast fibroadenomaMagnetic resonance imagingDifferential diagnosis

许莉、吴杰、任朝胚

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六盘水市人民医院 贵州 六盘水 553000

乳腺叶状肿瘤 乳腺纤维腺瘤 磁共振成像 鉴别诊断

2024

中外医学研究
中国医院管理杂志社

中外医学研究

影响因子:1.149
ISSN:1674-6805
年,卷(期):2024.22(20)