目的:探讨"三低三不"饮食原则联合高强度间歇有氧运动对老年糖尿病伴高脂血症患者的影响.方法:选取 2022 年 8 月—2023 年 8 月厦门大学附属第一医院收治的 102 例老年糖尿病伴高脂血症患者.随机将其分为对照组与观察组,各 51 例.对照组给予"三低三不"饮食原则联合中低强度持续有氧运动,观察组给予"三低三不"饮食原则联合高强度间歇有氧运动.比较两组干预前后的血糖指标、血脂指标、体格指标、血管内皮功能指标.结果:干预后,两组空腹血糖(FBG)、餐后 2 h血糖(2 h PG)均低于干预前,观察组FBG、2 h PG均低于对照组,差异有统计学意义(P<0.05).干预后,两组总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(lLDL-C)均低于干预前,HDL-C高于干预前,观察组TC、TG、LDL-C均低于对照组,HDL-C高于对照组,差异有统计学意义(P<0.05).干预后,两组体重、体重指数及腰围均低于干预前,观察组体重、体重指数及腰围均低于对照组,差异有统计学意义(P<0.05).干预后,两组内皮素(ET-1)低于干预前,一氧化氮(NO)高于干预前,观察组ET-1 低于对照组,NO高于对照组,差异有统计学意义(P<0.05).结论:"三低三不"饮食原则联合高强度间歇有氧运动能够降低老年糖尿病伴高脂血症患者的血糖血脂水平,降低其体格指标,改善其血管内皮功能.
Effect of"Three Low and Three No"Diet Principle Combined with High-intensity Intermittent Aerobic Exercise on Elderly Diabetes Patients with Hyperlipidemia
Objective:To explore the effect of"three low and three no"diet principle combined with high-intensity intermittent aerobic exercise on elderly diabetes patients with hyperlipidemia.Method:A total of 102 elderly diabetes patients with hyperlipidemia treated in the First Affiliated Hospital of Xiamen University from August 2022 to August 2023 were selected.They were randomly divided into control group and observation group,51 cases in each group.The control group was given the"three low three no"diet principle combined with medium-low intensity continuous aerobic exercise,and the observation group was given the"three low three no"diet principle combined with high-intensity intermittent aerobic exercise.Blood glucose index,blood lipid index,physical index and vascular endothelial function index were compared between the two groups before and after intervention.Result:After intervention,fasting blood glucose(FBG)and 2 h postprandial blood glucose(2 h PG)in both groups were lower than those before intervention,and FBG and 2 h PG in observation group were lower than those in control group,the differences were statistically significant(P<0.05).After intervention,total cholesterol(TC),triglyceride(TG),high density lipoprotein cholesterol(HDL-C)and low density lipoprotein cholesterol(lLDL-C)in both groups were lower than those before intervention,and HDL-C was higher than that before intervention,TC,TG and LDL-C in observation group were lower than those in control group,and HDL-C was higher than that in control group,the differences were statistically significant(P<0.05).After intervention,the body weight,body mass index and waist circumference of the two groups were lower than those before intervention,and the body weight,body mass index and waist circumference of the observation group were lower than those of the control group,the differences were statistically significant(P<0.05).After intervention,endothelin(ET-1)was lower than that before intervention,nitric oxide(NO)was higher than that before intervention,ET-1 in observation group was lower than that in control group,NO was higher than that in control group,the differences were statistically significant(P<0.05).Conclusion:The principle of"three low and three no"diet combined with high-intensity intermittent aerobic exercise can reduce blood glucose and lipid levels of elderly diabetes patients with hyperlipidemia,reduce physical indexes and improve vascular endothelial function in diabetic patients with hyperlipidemia.
Principle of"three low and three no"dietHigh intensity intermittent aerobic exerciseDiabetesHyperlipidemia
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