首页|非接触式全视野镜在增生期糖尿病性视网膜病变患者治疗中的临床效果

非接触式全视野镜在增生期糖尿病性视网膜病变患者治疗中的临床效果

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目的:分析非接触式全视野镜在增生期糖尿病性视网膜病变(PDR)患者治疗中的临床效果.方法:选取 2019年 1 月—2023 年 6 月荆州市第三人民医院收治的 120 例PDR患者作为研究对象,共 240 眼.根据随机数表法分为试验组和对照组,每组各 60 例.对照组使用 25 G玻璃体切除系统行微创玻璃体切除术,试验组在对照组基础上联合使用非接触式全视野镜.比较两组患者围手术期指标、最佳矫正视力(BCVA)、黄斑中心视网膜厚度(CMT)、血管内皮生长因子(VEGF)、内皮素(ET)-1 水平及术后并发症情况.结果:试验组手术时间明显少于对照组,差异有统计学意义(P<0.05);试验组治疗后BCVA、CMT数值明显低于对照组,差异有统计学意义(P<0.05);试验组治疗后VEGF、ET-1 水平明显低于对照组,差异有统计学意义(P<0.05);试验组并发症总发生率为 5.00%,对照组为 9.17%,试验组低于对照组,差异无统计学意义(P>0.05).结论:将非接触式全视野镜应用于PDR患者治疗中有利于缩短手术时间,提高术后视力,降低VEGF、ET-1 水平,安全可行.
Clinical Effect of Noncontact Panoramic Viewing System in the Treatment of Patients with Proliferative Diabetic Retinopathy
Objective:To analyze the clinical effect of noncontact panoramic viewing system in the treatment of patients with proliferative diabetic retinopathy(PDR).Method:120 patients(240 eyes)with PDR who were admitted to the Third People's Hospital of Jingzhou from January 2019 to June 2023 were selected as the study subjects.They were divided into the treatment group and the control group using the random number table method,with 60 cases(120 eyes)in each group.The control group was treated with minimally invasive vitrectomy using a 25G vitrectomy system.On this basis,the treatment group was treated with the noncontact panoramic viewing system.The perioperative indicators,best corrected visual acuity(BCVA),central macular thickness(CMT),vascular endothelial growth factor(VEGF)and endothelin-1(ET-1)levels,and postoperative complications were compared between the two groups.Result:Surgical time of the treatment group was significantly shorter than that of the control group,with a statistically significant difference(P<0.05).After treatment,BCVA,CMT,VEGF and ET-1 levels of the treatment group were significantly lower than those of the control group,with statistically significant differences(P<0.05).The overall complications which rate was 500%in the treatment group which was lower than that in the control group,but the difference was not statistically significant(P>0.05).Conclusion:Applying the noncontact panoramic viewing system in the treatment of patients with PDR,which is conducive to shorten surgical time,improve postoperative vision,and reduce VEGF and ET-1 levels.It is safe and feasible.

Noncontact panoramic viewing systemProliferative diabetiVitrectomyClinical effectVision

许雪玲、齐奇、胡琪

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荆州市第三人民医院 湖北 荆州 434000

非接触式全视野镜 增生期糖尿病性视网膜病变 玻璃体切割术 临床效果 视力

2024

中外医学研究
中国医院管理杂志社

中外医学研究

影响因子:1.149
ISSN:1674-6805
年,卷(期):2024.22(21)