Effectiveness of Transbronchial Isoarterial Chemoembolization in Non-surgical Elderly Patients over 70 Years Old with Lung Cancer
Objective:To investigate the efficacy of transbronchial isoarterial chemoembolization in non-surgical elderly patients over 70 years old with lung cancer.Method:The clinical data of 84 non-surgical elderly lung cancer patients over 70 years old admitted to the Department of Interventional and Vascular Surgery of Naval Anqing Hospital from November 2021 to June 2023 were retrospectively analyzed,and the patients were divided into the control group and the experimental group according to their treatment,with 4 cases in each group.Patients in the control group received intravenous chemotherapy,and patients in the experimental group received transbronchial and other arterial chemoembolization treatment.The treatment effect,lung function,tumor factor level and the occurrence of toxic side effects before and after treatment were compared between the two groups.Result:Disease Control Rate(DCR)of patients in the test group was higher than that of the control group,and the difference was statistically significant(P<0.05).After treatment,the lung function condition of patients in the test group was better than that of the control group,and the difference was statistically significant(P<0.05).After treatment,the levels of carcinoembryonic antigen(CEA),glycan antigen 125(CA125)and soluble fragment of cytokeratin 19(CYFRA21-1)in the test group were lower than those in the control group,and the difference was statistically significant(P<0.05).The incidence of toxic side effects in patients in the test group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion:The efficacy of transbronchial and other arterial chemoembolization for the treatment of non-surgical elderly lung cancer over 70 years old is better than that of intravenous chemotherapy,which can effectively improve the lung function of the patients,reduce the level of tumor factor in the patients'organisms,and at the same time,can alleviate the toxic side-effects produced by the treatment.
Lung cancerElderlyIntravenous chemotherapyArterial chemoembolizationTumor factorsToxic side effects
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