The Effect of Zishen Yutai Pill Combined with Phloroglucinol on Patients with Threatened Miscarriage
Objective:To explore the clinical effect of Zishen Yutai pill combined with phloroglucinol in the treatment of threatened miscarriage patients.Method:85 patients with threatened miscarriage admitted to Wuhan Huake Reproductive Hospital from July 2020 to December 2022 were randomly divided into a control group of 42 cases and an observation group of 43 cases using a random number table method.The control group was treated with phloroglucinol,while the observation group was treated with a combination of Zishen Yutai Pill.The effect was evaluated after one month of treatment.The clinical efficacy,serum sex hormone levels,symptom improvement,coagulation and fibrinolysis system function,fetal protection outcomes and adverse reactions were compared between two groups.Result:The total effective rate of the observation group was higher than that of the control group,the duration of vaginal bleeding,abdominal distension,abdominal pain and low back pain were shorter than those in the control group.The amount of vaginal bleeding was less than that of the control group Serum chorionic gonadotropin(β-HCG),estradiol(E2),and progesterone(P)were all higher in observation group than those in the control group,follicle estrogen(FSH)was lower than the control group after treatment,prothrombin time(PT)and activated partial thromboplastin time(APTT)were longer than those of the control group,fibrinogen(FIB),plasminogen activator inhibitor-1(PAI-1),and tissue plasminogen activator(t-PA)were lower than those of control group.The success rate of maintaining pregnancy in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).There was no statistically significant difference in adverse reactions between the two groups(P>0.05).Conclusion:The combination of Zishen Yutai pill and phloroglucinol in the treatment of threatened miscarriage patients can effectively regulate serum sex hormone levels,improve coagulation and fibrinolysis system function,accelerate clinical symptom recovery,increase the success rate of fetal protection,and is safe and reliable.
Threatened miscarriageZishen Yutai pillPhlorotriolSerum sex hormone levelsImprovement of symptomsCoagulation and fibrinolysis system functionThe outcome of protecting the fetus
国家科技期刊平台
NSTL
万方数据
