Effect of Gastrodin Capsules Combined with Carbamazepine Tablets in the Treatment of Patients with Primary Trigeminal Neuralgia
Objective:To explore the effect of Gastrodin Capsules combined with Carbamazepine Tablets in the treatment of patients with primary trigeminal neuralgia.Method:A total of 70 patients with primary trigeminal neuralgia who treated in Zhejiang Provincial People's Hospital Bijie Hospital from January 2021 to December 2023 were selected as the research objects,the patients were divided into the observation group and the control group by random number table method,with 35 cases in each group.The control group was treated with Carbamazepine Tablets,and the observation group was treated with Gastrodin Capsules combined with Carbamazepine Tablets,two groups were treated for 20 d.The clinical efficacy,pain degree,sleep quality,serum related indexes and adverse reactions were compared between two groups.Result:The total effective rate of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).After treatment,the visual analogue score(VAS)score,Pittsburgh sleep quality index(PSQI)score,the levels of tumor necrosis factor-α(TNF-α)and nerve growth factor(NGF)in two groups were lower than those before treatment,and those in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).There was no significant difference in the total incidence of adverse reactions between two groups(P>0.05).Conclusion:Gastrodin Capsules combined with Carbamazepine Tablets in the treatment of primary trigeminal neuralgia has a significant effect,which can relieve pain,improve sleep quality,regulate serum factor levels,and has high safety.
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