Effect of Ultrasound-guided Dexmedetomidine Combined with Ropivacaine TAPB on Patients Undergoing Laparoscopic Radical Gastrectomy for Gastric Cancer
Objective:To investigate the effect of ultrasound-guided Dexmedetomidine combined with Ropivacaine transversus abdominalis plane block(TAPB)on patients undergoing laparoscopic radical gastrectomy for gastric cancer.Method:A total of 64 patients who underwent laparoscopic radical gastrectomy for gastric cancer in Zhangzhou Affiliated Hospital of Fujian Medical University from January 2020 to March 2023 were selected and divided into group A(n=32)and group B(n=32)according to different anesthesia programs.Both groups were given general anesthesia.On this basis,ultrasound-guided Ropivacaine TAPB was used in group B,and ultrasound-guided Dexmedetomidine combined with Ropivacaine TAPB was used in group A.The mean arterial pressure(MAP)and heart rate(HR)before anesthesia induction(T0),during endotracheal intubation(T1),block(T2),skin resection(T3),extubation(T4),and the Ramsay sedation scale(RSS)scores and visual analogue scale(VAS)scores at 6 h,12 h and 24 h after surgery,and the occurrence of adverse reactions were compared between the two groups.Result:There were no significant differences of MAP,HR at T0,T4 between the two groups(P>0.05).T1,T2,T3,MAP and HR in group A were lower than those in group B,and the differences were statistically significant(P<0.05).At 6 h,12 h and 24 h after surgery,the RSS scores and VAS scores of group A were lower than those of group B,and the differences were statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between group A and group B(P>0.05).Conclusion:Ultrasound-guided Dexmedetomidine combined with Ropivacaine TAPB has a good anesthetic effect in patients undergoing laparoscopic radical gastrectomy for gastric cancer.The intraoperative blood flow fluctuation of patients is small,and adverse reactions are not significantly increased,and with high safety.
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