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宫腔镜下电切术联合屈螺酮炔雌醇治疗子宫内膜息肉不孕症的效果

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目的:探究宫腔镜下电切术联合屈螺酮炔雌醇治疗子宫内膜息肉不孕症的效果。方法:前瞻性选取 2021 年10 月—2022年10月新泰市人民医院收治的104例子宫内膜息肉不孕症患者,按手术方法不同分为研究组52例和对照组52例。对照组采取宫腔镜下刮宫术治疗,研究组采取宫腔镜下电切术治疗,且两组均联合屈螺酮炔雌醇治疗,治疗 3 个周期。比较两组临床疗效、月经失血图(pictorial blood loss assessment chart,PBAC)评分、子宫内膜厚度、并发症、复发率及妊娠率。结果:研究组疗效、总有效率均高于对照组,差异有统计学意义(P<0。05)。术后 3 个周期,两组PBAC评分低于术前,且研究组PBAC评分低于对照组,差异有统计学意义(P<0。05)。术后 3 个周期,两组子宫内膜厚度低于术前,且研究组子宫内膜厚度低于对照组,差异有统计学意义(P<0。05)。两组宫颈狭窄、子宫粘连、宫内感染等并发症总发生率比较,差异无统计学意义(P>0。05)。研究组术后 6 个月、12 个月复发率低于对照组,妊娠率均高于对照组,差异有统计学意义(P<0。05)。结论:宫腔镜下电切术联合屈螺酮炔雌醇治疗子宫内膜息肉不孕症临床效果更好,可有效改善患者PBAC评分与子宫内膜厚度,降低复发率,提高妊娠率,且安全性较好。
Effect of Hysteroscopic Resection Combined with Drospirenone Ethinylestradiol in the Treatment of Patients with Infertility of Endometrial Polyps
Objective:To explore the effect of hysteroscopic electroresection combined with Drospirenone Ethinylestradiol in patients with infertile of endometrial polyps.Method:A total of 104 patients of infertility of endometrial polyp admitted to Xintai People's Hospital from October 2021 to October 2022 were prospectively selected.According to different operation method,they were divided into research group of 52 cases and control group of 52 cases.The control group used hysteroscopic curettage treatment,and the research group used hysteroscopic resection treatment,and both groups were treated combined with Drospirenone Ethinylestradiol.The treatment was 3 cycles.The clinical efficacy,pictorial blood loss assessment chart(PBAC)score,endometrial thickness,complications,recurrence rate and pregnancy rate were compared between the two groups.Result:The efficacy and total effective rate of the research group were higher than that of the control group,and the difference was statistically significant(P<0.05).In 3 cycles after operation,the PBAC scores of the two groups were lower than that of the preoperative period,and the PBAC score of the research group was lower than that of the control group,and the differences were statistically significant(P<0.05).In 3 postoperative cycles,the endometrial thickness of both groups was lower than that of preoperative,and the endometrial thickness of the research group was lower than that of the control group,and the differences were statistically significant(P<0.05).There was no significant difference in the total incidence of complications such as cervical stenosis,uterine adhesion and intrauterine infection between the two groups(P>0.05).The recurrence rates of the research group at 6 months and 12 months after surgery were lower than those of the control group,and the pregnancy rates were higher than those of the control group,the differences were statistically significant(P<0.05).Conclusion:Hysteroscopic electroresection combined with Drospirenone Ethinylestradiol has better clinical effect in the treatment of infertility of endometrial polyps,which can effectively improve PBAC score and endometrial thickness in patients,reduce recurrence rate,improve pregnancy rate,and have better safety.

Infertility of endometrial polypsHysteroscopic electrodissectionHysteroscopic curettageDrospirenone EthinylestradiolTreatment effectPregnancy outcome

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新泰市人民医院 山东 新泰 271200

子宫内膜息肉不孕症 宫腔镜下电切术 宫腔镜下刮宫术 屈螺酮炔雌醇 治疗效果 妊娠结局

2024

中外医学研究
中国医院管理杂志社

中外医学研究

影响因子:1.149
ISSN:1674-6805
年,卷(期):2024.22(23)