首页|心境障碍与白细胞介素-6关系的研究进展

心境障碍与白细胞介素-6关系的研究进展

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目前心境障碍发病机制与免疫炎症的关系尚不明确,越来越多证据显示心境障碍的病理生理机制与免疫炎症通路失调有关,大部分研究表明心境障碍促炎性细胞因子,比如白细胞介素-6(IL-6)在外周血的浓度升高。本文对心境障碍与IL-6 的关系进行总结,以探索IL-6 是否可以成为诊断双相障碍和抑郁症的生物标志物,为心境障碍的早期诊断和规范治疗提供重要参考。
Research Progress on the Relationship between Mood Disorders and Interleukin-6
At present,the relationship between the pathogenesis of mood disorders and immune inflammation is still unclear.More and more evidence shows that the pathophysiological mechanism of mood disorders is related to the dysregulation of immune inflammatory pathways.Most studies show that the concentration of pro-inflammatory cytokines such as interleukin-6(IL-6)in peripheral blood of mood disorders increases.This paper summarizes the relationship between mood disorders and IL-6,so as to explore whether IL-6 can be used as a biomarker for the diagnosis of bipolar disorder and depression,and provide important references for the early diagnosis and standardized treatment of mood disorders.

Mood disordersBipolar disorderDepressionInterleukin-6

杨春虹、李春阳

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广东医科大学 广东 湛江 524023

佛山市顺德区伍仲珮纪念医院

心境障碍 双相障碍 抑郁症 白细胞介素-6

佛山市卫生健康局医学科研课题立项项目

20240720A010618

2024

中外医学研究
中国医院管理杂志社

中外医学研究

影响因子:1.149
ISSN:1674-6805
年,卷(期):2024.22(23)