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我院重症监护室肺部感染菌群特征及影响因素分析

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目的:探讨阜宁县人民医院重症监护室(ICU)患者的肺部感染菌的特征及其影响因素.方法:回顾性地分析2021 年 6 月—2023 年 7 月阜宁县人民医院不同科室重症监护室收治的 1 682 例患者的临床资料,统计肺部感染菌的种群分布情况.采用随机数表法从感染患者(n=108)和非感染患者(n=1 574)中各随机抽取 70 例患者作为感染组(n=70)与非感染组(n=70),对所选样本采用单因素和多因素logistic回归分析ICU患者肺部感染的重要影响因素.结果:3 年内,在 1 682 例ICU患者中,发生肺部病原菌感染者 108 例.从感染的患者体内共分离出病原菌共计 205 株,其中革兰氏阴性菌147 株(71.7%),阳性菌 30 株(14.6%),真菌 28 株(13.7%).通过单因素和多因素logistic回归分析,ICU患者肺部病原菌感染与多种主要因素有关,其中包括ICU住院时间、广谱抗菌药物使用天数、糖皮质激素应用时间、是否使用气管插管、是否留置尿管气管插管、基础疾病.结论:ICU感染菌群以革兰氏阴性菌为主.引发ICU患者肺部感染的主要因素为ICU住院时间、广谱抗菌药物使用天数、糖皮质激素应用时间、是否使用气管插管、是否留置尿管气管插管、基础疾病种类数.
Analysis of the Characteristics and Influencing Factors of Pulmonary Infection Pathogens in the Intensive Care Unit of the People's Hospital of Funing County
Objective:To investigate the characteristics and influencing factors of pulmonary infections in ICU patients at Funing County People's Hospital.Method:A retrospective analysis of clinical data of 1 682 ICU patients from various departments from June 2021 to July 2023,focusing on the distribution of pulmonary pathogens.70 patients were randomly selected from 108 infected patients and 1 574 non-infected patients as infected group consisted of 70 cases and non-infected group consisted of 70 cases by random number table method.Univariate and multivariate logistic regression analyses were applied to determine significant factors influencing pulmonary infections in ICU patients.Result:Within three years,among 1682 ICU patients,108 developed pulmonary pathogen infections.A total of 205 pathogens were isolated,including 147 Gram-negative bacteria(71.7%),30 Gram-positive bacteria(14.6%)and 28 fungi(13.7%).The analysis revealed that ICU stay duration,broad-spectrum antibiotic use duration,corticosteroid use duration,intubation,indwelling catheter use,and underlying diseases were significant factors.Conclusion:The ICU infections were predominantly caused by Gram-negative bacteria.Major factors leading to pulmonary infections in ICU patients included ICU stay duration,use of broad-spectrum antibiotics,corticosteroid application,intubation,and underlying diseases.

Intensive care unitPulmonary infection pathogensInfluencing factors

曾凤、李强、杨健

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阜宁县人民医院 江苏 阜宁 224400

重症监护室 肺部感染菌群 影响因素

2024

中外医学研究
中国医院管理杂志社

中外医学研究

影响因子:1.149
ISSN:1674-6805
年,卷(期):2024.22(24)