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左侧后入路和右侧前入路腹腔镜胃癌根治术的临床疗效比较

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目的:比较右侧前入路和左侧后入路腹腔镜胃癌根治术的临床疗效.方法:选择 2022 年 1 月—2024 年 1 月在福建中医药大学附属第二人民医院进行手术治疗的 80 例胃癌患者作为研究对象,按手术方式不同分为试验组(n=40)和对照组(n=40).所有患者均实施腹腔镜胃癌根治术,试验组采用右侧前入路,对照组采用左侧后入路.比较两组手术和康复指标(手术用时、术中出血量、淋巴结清扫数量、住院总时长和术后排气时间)、胃肠功能评分、血清炎症因子[超敏C反应蛋白(hs-CRP)、白细胞介素-6(IL-6)]与癌胚抗原(CEA)水平及术后 3 个月内并发症(切口感染、肺部感染、肠梗阻和术后胃瘫)发生情况.结果:试验组手术用时、术中出血量、住院总时长和术后排气时间优于对照组,淋巴结清扫数量多于对照组,差异有统计学意义(P<0.05).术前,两组胃肠功能评分及血清炎症因子、CEA水平比较,差异无统计学意义(P>0.05);术后 7 d,两组胃肠功能评分较术前下降,且试验组低于对照组,差异有统计学意义(P<0.05);术后 3 d,两组hs-CRP、IL-6 水平较治疗前升高,但试验组低于对照组,两组CEA水平较术前降低,且试验组低于对照组,差异有统计学意义(P<0.05).试验组术后 3 个月内并发症发生率低于对照组,差异无统计学意义(P>0.05).结论:相较于左侧后入路腹腔镜胃癌根治术,右侧前入路腹腔镜胃癌根治术具有许多方面的优势,包括手术视野开阔、淋巴结清扫彻底、炎症因子水平更低、术中损伤更少、术后恢复速度更快,可以提高整体治疗效果和促进患者更快康复.
Comparison of Clinical Efficacy between Left Posterior Approach and Right Anterior Approach in Laparoscopic Radical Gastrectomy for Gastric Cancer
Objective:To compare the clinical efficacy of right anterior approach and left posterior approach in laparoscopic radical gastrectomy for gastric cancer.Method:A total of 80 patients with gastric cancer who underwent surgical treatment in the Second People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine from January 2022 to January 2024 were selected as the research objects,they were divided into the experimental group(n=40)and the control group(n=40)according to different surgical methods.All patients were underwent laparoscopic radical gastrectomy,the experimental group was treated with right anterior approach,and the control group was treated with left posterior approach.The operation and rehabilitation indexes(operation time,intraoperative blood loss,number of lymph node dissection,total hospitalization time and postoperative exhaust time),gastrointestinal function scores,serum inflammatory factors[high-sensitivity C-reactive protein(hs-CRP),interleukin-6(IL-6)]and carcinoembryonic antigen(CEA)levels and complications(incision infection,pulmonary infection,intestinal obstruction and postoperative gastroparesis)within 3 months after operation were compared between two groups.Result:The operation time,intraoperative blood loss,total hospitalization time and postoperative exhaust time of the experimental group were better than those of the control group,and the number of lymph node dissection was more than that of the control group,the differences were statistically significant(P<0.05).Before operation,there were no significant differences in the gastrointestinal function scores,serum inflammatory factors and CEA levels between two groups(P>0.05);at 7 d after operation,the gastrointestinal function scores in two groups were lower than those before operation,and that in the experimental group was lower than that in the control group,the differences were statistically significant(P<0.05);at 3 d after operation,the levels of hs-CRP and IL-6 in two groups were higher than those before treatment,but those in the experimental group were lower than the control group,the levels of CEA in two groups were lower than those before operation,and that in the experimental group was lower than that in the control group,the differences were statistically significant(P<0.05).The incidence of complications in the experimental group within 3 months after operation was lower than that in the control group,and the difference was not statistically significant(P>0.05).Conclusion:Compared with laparoscopic radical gastrectomy via left posterior approach,laparoscopic radical gastrectomy via right anterior approach has many advantages,including open surgical field,thorough lymph node dissection,lower level of inflammatory factors,less intraoperative injury,faster postoperative recovery,which can improve the overall treatment effect and promote faster recovery of patients.

Left posterior approachRight anterior approachLaparoscopic radical gastrectomy for gastric cancerClinical efficacy

李强

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福建中医药大学附属第二人民医院 福建 福州 350003

左侧后入路 右侧前入路 腹腔镜胃癌根治术 临床疗效

2024

中外医学研究
中国医院管理杂志社

中外医学研究

影响因子:1.149
ISSN:1674-6805
年,卷(期):2024.22(25)