Analysis of Sputum Pathogen Culture and Drug Susceptibility Test in Elderly Bronchiectasis with Pulmonary Infection
Objective:To explore the results of sputum pathogen culture and drug susceptibility test in elderly patients with bronchiectasis combined with pulmonary infection.Method:Eighty-nine elderly patients with bronchiectasis combined with pulmonary infection admitted to Zunyi City Bozhou District Hospital of Traditional Chinese Medicine from January 2021 to December 2023 were selected as the study objects.Sputum samples were collected for examination,pathogen culture and drug susceptibility test were performed.The detection and drug resistance of pathogenic bacteria were analyzed.Result:A total of 97 strains of pathogenic bacteria were isolated from 89 patients,of which 61 strains(62.89%)were Gram-negative bacilli,the top three were Pseudomonas aeruginosa(29.90%),Klebsiella pneumoniae(18.56%)and Escherichia coli(14.43%).32 strains(32.99%)of Gram-positive cocci were detected,the top three were Staphylococcus aureus(10.31%),Staphylococcus epidermidis(8.25%)and Streptococcus pneumoniae(6.19%).Four strains(4.12%)were fungi.The main Gram-negative bacteria were not resistant to Ertapenem and Imipenem.Escherichia coli had high resistance to Cefuroxime and Ceftriaxone.The main Gram-positive bacteria had no resistance to Vancomycin,Linezolid and Teicolanin,among which Staphylococcus aureus and Staphylococcus epidermidis had high resistance to Penicillin and Erythromycin.Conclusion:The sputum pathogens in elderly patients with bronchiectasis and pulmonary infection are mainly Gram-negative bacteria,with a small amount of fungi,so drugs should actively refer to the results of drug sensitivity to better promote the disappearance of infection.
BronchiectasisPulmonary infectionPathogen cultureDrug susceptibility test