Application Effect of Remimazolam Combined with Ciprofol in Elderly Patients Undergoing Painless Colonoscopy
Objective:To analyze the application effect of Remimazolam combined with Ciprofol in elderly patients undergoing painless colonoscopy.Method:A total of 120 elderly patients with painless colonoscopy admitted to Changsha Hospital of Traditional Chinese Medicine from January to April 2024 were selected.According to the method of random number table,they were randomly divided into observation group and control group,60 cases in each group.The observation group was given Remimazolam combined with Ciprofol anesthesia,and the control group was given Ciprofol anesthesia.The vital signs before anesthesia(T1),colonoscopy through the anus(T2),colonoscopy to the ileocecal part(T3),at the end of the examination(T4),anesthesia indexes and adverse reactions of two groups were compared.Result:The mean arterial pressure(MAP)of T2,T3 and T4 in observation group was higher than that in control group,the heart rate(HR)of T2,T3 in observation group was higher than that in control group,and the percutaneous blood oxygen saturation(SpO2)of T2 was higher than that of control group,and the differences were statistically significant(P<0.05).The MAP at T2,T3,T4 of two groups were lower than that at T1 in this group;HR at T2 and T3 in two groups were lower than T1 in this group;SpO2 at T2 in two groups was lower than at T1 in this group,and the differences were statistically significant(P<0.05).The onset time of anesthesia,recovery time and leaving the room time in the observation group were significantly earlier than those in the control group,and the differences were statistically significant(P<0.05).The incidences of hypotension and respiratory depression in observation group were lower than those in control group,and the differences were statistically significant(P<0.05).Conclusion:Remimazolam combined with Ciprofol is safe and effective in elderly patients with painless colonoscopy,can reduce adverse reactions,and can shorten the onset time,recovery time and exit time.
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