Effects of Inhaled Nitric Oxide on Persistent Neonatal Pulmonary Hypertension
Objective:To analyze the effect of inhaled nitric oxide(NO)in neonatal persistent pulmonary hypertension(PPHN).Method:A total of 70 children with PPHN admitted to Tongren People's Hospital from January 2021 to December 2023 were selected,and they were divided into control group and observation group according to the random number table method,35 cases in each group.Both group received symptomatic treatment.On this basis,the control group used constant frequency mechanical ventilation,and the observation group used constant frequency mechanical ventilation combined with inhalation NO treatment.By comparing the oxygen supply status of the two groups,the clinical treatment efficiency and recovery of the two groups were counted.Result:After treatment,the blood oxygen saturation,blood oxygen partial pressure level and the total response rate of the observation group were higher than that of the control group,the differences were statistically significant(P<0.05).In the observation group,the hospital stay,duration of oxygen therapy and the relief of dyspnea were shorter than that in the control group,and the pulmonary artery pressure level was lower than that in the control group,the differences were statistically significant(P<0.05).Conclusion:Inhalation NO treatment in children with PPHN can improve their blood oxygen status,accelerate the relief rate of dyspnea symptoms,reduce pulmonary artery pressure,shorten the length of treatment and hospital stay,and enhance the treatment effect.
Neonatal persistent pulmonary hypertensionInhaled nitric oxideOxygen supply status
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