Effect of Modified Xiaoqinglong Decoction Combined with Levocetirizine Hydrochloride in Adult Rhinitis Patients
Objective:To explore the clinical effect of modified Xiaoqinglong Decoction combined with Levocetirizine Hydrochloride in the treatment of adult nasal allergy.Method:From January 2019 to January 2023,a total of 102 adult patients diagnosed with allergic rhinitis were admitted to Hai'an Traditional Chinese Medicine Hospital were selected.The patients were divided into two groups according to the random number table method,with each group consisting of 51 cases.The control group received treatment with Levocetirizine Hydrochloride,while the observation group treatment with modified Xiaoqinglong Decoction,both groups underwent a four-week treatment.The clinical efficacy,clinical symptom scores,serum immunoglobulin E(IgE)levels,inflammatory factor levels,quality of life,and adverse reactions were compared between the two groups.Result:The total effective rate of treatment in the observation group was higher than that of the control group,the difference was statistically significant(P<0.05).After treatment,the observation group exhibited lower scores for nasal congestion,runny nose,nasal itching and sneezing than those in the control group,the differences were statistically significant(P<0.05).After treatment,the IgE,interleukin-4(IL-4),interleukin-6(IL-6)in the observation group were lower than those in the control,but interferon-γ(IFN-γ)was higher than that in the control group,the differences were statistically significant(P<0.05).After treatment,the scores of physical,psychological,social and environmental fields in the observation group were higher than those in the control group,the differences were statistically significant(P<0.05).There was no significant difference in adverse reactions between the two groups(P>0.05).Conclusion:The combination of modified Xiaoqinglong Decoction combined with Levocetirizine Hydrochloride can improve the treatment effect of adult nasal allergy,accelerate the disappearance of clinical symptoms,reduce serum IgE and inflammatory factor levels,alleviate the impact of the disease on daily life.
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