The Effect of Thoracoscopic Lung Segmentectomy in the Treatment of Elderly Patients with Early Non-small Cell Lung Cancer
Objective:To explore the efficacy of thoracoscopic lung segmentectomy in the treatment of elderly patients with early Non-small Cell Lung Cancer(NSCLC).Method:80 early NSCLC patients admitted to Zibo Infectious Disease Hospital from March 2020 to August 2023 were selected and divided into two groups using a random number table method,with 40 cases in each group.The control group underwent thoracoscopic lobectomy,while the observation group underwent thoracoscopic segmental resection.The perioperative related indicators,lung function indicators,stress indicators,immune function and complications were compared between two groups.Result:The observation group had a longer surgical time,less intraoperative bleeding,less postoperative drainage volume,and shorter postoperative drainage and hospitalization time compared the control group,with statistical significance(P<0.05).The postoperative Forced Vital Capacity(FVC),first second Forced Expiratory Volume(FEV1)in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).The postoperative levels of norepinephrine(NE),cortisol(COR)and Adrenocorticotropic Hormone(ACTH)in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).The postoperative CD3+,CD4+,CD4+/CD8+levels in the observation group were higher than those in the control group,while CD8+levels were lower than those in the control group,with statistically significant differences(P<0.05).There was no statistically significant difference in comparison of complication rare between the two groups(P>0.05).Conclusion:Thoracoscopic segmental resection is more effective in the treatment of elderly patients with early NSCLC,which can reduce surgical trauma,protect lung function and immune function of patients,and it is safe and reliable.
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