Analysis of Serum Specific IgE Test Results in Children with Allergic Diseases in Changle District of Fuzhou City
Objective:To analyze the detection results of serum specific immunoglobulin E(IgE)in children with allergic diseases in Changle District of Fuzhou City,and to providing an accurate basis for clinical treatment and prevention of allergic diseases in children.Method:A total of 4 802 patients who visited Fuzhou Changle Women and Children's Hospital from July 1,2020 to March 20,2023 and tested for specific IgE(sIgE)were retrospectively included,the allergen test results of 4 802 patients were counted,and the positive rates of common allergens in different populations,seasons,clinical symptoms and age groups were compared.Result:A total of 13 214 sIgE tests were conducted in Changle District of Fuzhou City,and 5 427 were positive,with an overall positive detection rate of 41.1%.Among them,5 304 were mixed inhalant allergens,accounting for 40.1%of total,and the positive detection rate was 42.2%(2 240/5 304).A total of 7 910 mixed food allergens were detected,accounting for 59.9%of the total detection,and the positive detection rate was 40.3%(3 187/7 910).The detection items with the highest positive rate in children with allergic diseases in this region were hx2(72.4%),fx5(51.2%),f2(68.1%)and f1(56.9%).Male children were more susceptible than female children,and male children were more likely to be positive for inhalant allergens than food allergens.The peak of positive rate of outdoor allergens appeared in April,June,July,August,September and October.The symptoms with the highest positive rate were eye symptoms and respiratory symptoms.The symptoms with higher positive rate of inhaled allergens than food allergens were respiratory symptoms and eye symptoms.The symptoms with higher positive rate of food allergens than inhaled allergens were skin symptoms and gastrointestinal symptoms.Conclusion:The ingestive allergens of children in Changle District of Fuzhou City are mainly milk and egg protein,and the inhalation allergens are common in dust mite combinations.There are differences in the structure of allergens in different symptoms and different months.Therefore,it is necessary to understand the general situation of local allergen sensitization,formulate a combination of allergen detection suitable for local areas,effectively avoid allergens,and clarify that allergens can prevent and treat allergic diseases.
Allergic diseasesAllergen-specific diagnosisImmunoglobulin E
万方数据
维普
