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血尿酸与慢性阻塞性肺疾病相关性研究进展

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慢性阻塞性肺疾病(COPD)是一种常见的慢性呼吸系统疾病。其发生发展与炎症反应、氧化应激密切相关。而血清尿酸通过诱导内源性免疫细胞来增加炎症反应。尿酸在缺氧状态下会进一步升高,促进炎症及氧化应激反应,影响肺组织通气功能。血清尿酸水平可以作为评估患者病情严重程度、治疗效果及预后的重要指标,但其生物学机制仍需进一步研究证实。就此,本文综述血清尿酸与COPD疾病的关联。
Research Progress on Correlation between Serum Uric Acid and Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease(COPD)is a common chronic respiratory system disease.Its occurrence and development are closely related to inflammatory reactions and oxidative stress.Serum uric acid increases inflammatory reactions by inducing endogenous immune cells.Uric acid further increases in hypoxic conditions,promoting inflammation and oxidative stress reactions,affecting lung tissue ventilation function.Serum uric acid levels can serve as an important indicator for evaluating the severity of the patient's condition,treatment effectiveness,and prognosis,but its biological mechanism still requires further research confirmation.In this regard,this article reviews the association between serum uric acid and COPD.

Chronic obstructive pulmonary diseaseUric acidInflammatory responseOxidative stress

邹雨菲、胡涛

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扬州大学医学院 江苏 扬州 225000

扬州大学附属医院

慢性阻塞性肺病 血清尿酸 炎症反应 氧化应激

2024

中外医学研究
中国医院管理杂志社

中外医学研究

影响因子:1.149
ISSN:1674-6805
年,卷(期):2024.22(28)