Effect of Baoyuan Decoction Combined with Tingli Dazao Xiefei Decoction in the Treatment of Patients with Heart Failure with Reduced Ejection Fraction
Objective:To explore the effect of Baoyuan Decoction combined with Tingli Dazao Xiefei Decoction in the treatment of patients with heart failure with reduced ejection fraction (HFrEF).Method:A total of 60 patients with HFrEF who treated in Zhaoqing Traditional Chinese Medicine Hospital from July 2022 to December 2023 were selected as the study objects,they were randomly divided into the control group and the experimental group,with 30 cases in each group.The control group was given basic treatment of western medicine,the experimental group was treated with Baoyuan Decoction combined with Tingli Dazao Xiefei Decoction on the basis of the control group,the clinical effect,echocardiographic indexes,cardiac function indexes,quality of life and adverse reactions were compared between two groups.Result:The total effective rate of the experimental group was higher than that of the control group,and the difference was statistically significant (P<0.05);after treatment,the left ventricular end-systolic diameter (LVESD),left ventricular end-diastolic diameter (LVEDD) and N-terminal pro-brain natriuretic peptide (NT-proBNP) levels in two groups were lower than those before treatment,and those in the experimental group were lower than those in the control group,the left ventricular ejection fraction (LVEF) of two groups were higher than those before treatment,and that in the experimental group was higher than that in the control group,the differences were statistically significant (P<0.05);after treatment,the scores of physical fields,emotional fields and other fields in both groups were lower than before treatment,and the scores in the experimental group were lower than those in the control group,the differences were statistically significant (P<0.05);there was no significant difference in the incidence of adverse reactions between two groups during treatment (P>0.05).Conclusion:Baoyuan Decoction combined with Tingli Dazao Xiefei Decoction is effective in the treatment of patients with HFrEF,which can effectively improve cardiac function and improve left ventricular function,with good safety.
Baoyuan DecoctionTingli Dazao Xiefei DecoctionReduced ejection fractionHeart failureLeft heart function