首页|宫腔镜下冷刀切除术对子宫内膜息肉患者术后粘连及子宫内膜的影响研究

宫腔镜下冷刀切除术对子宫内膜息肉患者术后粘连及子宫内膜的影响研究

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目的:探究宫腔镜下冷刀切除术对子宫内膜息肉患者术后粘连及子宫内膜的影响。方法:将2019年12月—2022年12月泉州东南医院收治的90例子宫内膜息肉患者作为研究对象,根据随机数表法分为对照组与观察组,各45例。对照组进行宫腔镜下电切术治疗,观察组进行宫腔镜下冷刀切除术治疗。比较两组手术时间、术中出血量、住院时间、并发症发生率、术后宫腔粘连发生率及手术前后月经失血图(PBAC)评分、子宫内膜厚度、宫腔粘连指标[血清基质金属蛋白酶组织抑制因子1(TIMP1)、转化生长因子β1(TGF-β1)、结缔组织生长因子(CTGF)]及子宫内膜血流参数[脐动脉血流搏动指数(PI)、动脉血流阻力指数(RI)]。结果:观察组手术时间、住院时间短于对照组,术中出血量少于对照组,并发症发生率、术后宫腔粘连发生率低于对照组,差异有统计学意义(P<0。05);观察组术后1个月、3个月PBAC评分、子宫内膜厚度、宫腔粘连指标及子宫内膜血流参数低于对照组,差异有统计学意义(P<0。05)。结论:宫腔镜下冷刀切除术可有效降低子宫内膜息肉患者并发症、术后粘连发生率,对子宫内膜的影响相对更小。
Study on Influence of Cold-knife Resection by Hysteroscopy for Postoperative Adhesion and Endometrium of Patients with Endometrial Polyps
Objective:To investigate the influence of cold-knife resection by hysteroscopy for postoperative adhesion and endometrium of patients with endometrial polyps.Method:A total of 90 patients with endometrial polyps who admitted to Quanzhou Southeast Hospital from December 2019 to December 2022 were selected as the study objects,they were divided into the control group and the observation group according to random number table method,with 45 cases in each group.The control group was treated with electrocision by hysteroscopy,the observation group was treated with cold-knife resection by hysteroscopy.The operation time,intraoperative blood loss,hospitalization time,incidence of complications,incidence of postoperative intrauterine adhesions,pictorial blood loss assessment chart (PBAC) score,endometrial thickness,intrauterine adhesion index[serum tissue inhibitor of metalloproteinase 1 (TIMP1),transforming growth factor-β1 (TGF-β1),connective tissue growth factor (CTGF)]and endometrial blood flow parameters[umbilical artery blood flow pulsation index (PI),arterial blood flow resistance index (RI)]score before and after operation were compared between two groups.Result:The operation time and hospitalization time of the observation group were shorter than those of the control group,the intraoperative blood loss was less than that of the control group,the incidence of complications and the incidence of postoperative intrauterine adhesions were lower than those of the control group,the differences were statistically significant (P<0.05);the PBAC scores,endometrial thickness,intrauterine adhesion index and endometrial blood flow parameters of the observation group at 1 month and 3 months after operation were lower than those of the control group,and the differences were statistically significant (P<0.05).Conclusion:Cold-knife resection by hysteroscopy can effectively reduce the incidence of complications and postoperative adhesions in patients with endometrial polyps,and has a relatively small impact on endometrium.

Cold-knife resection by hysteroscopyEndometrial polypsPostoperative adhesionEndometrium

丁丽琴、江秀萍、殷质朴

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泉州东南医院 福建 泉州 362000

宫腔镜下冷刀切除术 子宫内膜息肉 术后粘连 子宫内膜

2024

中外医学研究
中国医院管理杂志社

中外医学研究

影响因子:1.149
ISSN:1674-6805
年,卷(期):2024.22(29)