中外医学研究2024,Vol.22Issue(29) :127-130.DOI:10.14033/j.cnki.cfmr.2024.29.031

小剂量多巴胺治疗老年慢性充血性心力衰竭的效果

Effect of Low Dose Dopamine in the Treatment of Chronic Congestive Heart Failure in Elderly Patients

温冬梅
中外医学研究2024,Vol.22Issue(29) :127-130.DOI:10.14033/j.cnki.cfmr.2024.29.031

小剂量多巴胺治疗老年慢性充血性心力衰竭的效果

Effect of Low Dose Dopamine in the Treatment of Chronic Congestive Heart Failure in Elderly Patients

温冬梅1
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作者信息

  • 1. 三明市第二医院 福建 永安 366000
  • 折叠

摘要

目的:探讨小剂量多巴胺治疗老年慢性充血性心力衰竭的效果.方法:从2021年1月—2022年12月三明市第二医院心血管内科收治的老年慢性充血性心力衰竭病例中纳入80例展开研究.根据随机数表法将其分为观察组、对照组,各40例.所有患者予以常规治疗,对照组给予注射用重组人脑利钠肽联合左西孟旦,观察组在对照组基础上给予小剂量多巴胺.比较两组临床疗效,治疗前后相关指标及时间指标.结果:总有效率经对比观察组病例更高,治疗后,两组24 h尿量升高,心率、呼吸频率、氨基末端脑利钠肽前体(NT-proBNP)均降低,观察组24 h尿量、心率、NT-proBNP等指标均低于对照组,心力衰竭好转时间和住院时间中,观察组短于对照组,差异有统计学意义(P<0.05).结论:小剂量多巴胺适用于慢性充血性心力衰竭的老年患者的治疗需求,可对患者的24 h尿量、心率指标有明显改善作用,还能提高疗效,缩短恢复时间.

Abstract

Objective:To investigate the effect of low dose Dopamine in the treatment of chronic congestive heart failure in elderly patients.Method:From January 2021 to December 2022,80 elderly patients with chronic heart failure in Department of Cardiovascular Medicine of the Second Hospital of Sanming were enrolled in the study.According to the standard of random number table,the patients were divided into observation group and control group,with 40 cases in each group.All the patients were treated with routine therapy.The control group was treated with Recombinant Human Brain Natriuretic peptide combined with Levosimendan.The observation group was given low-dose of Dopamine on the basic of the control group.The clinical effect,related indexes and time indexes before and after treatment were compared between the two groups.Result:The total effective rate in the observation group was higher than that in the control group,after treatment,24 h urine volume increased,heart rate,respiratory rate and amino terminal brain natriuretic peptide precursor (NT-proBNP) decreased in both groups,the 24 h urine volume,heart rate and NT-proBNP in the observation group were lower than those in the control group,the improvement of heart failure and the time of hospitalization in the observation group were shorter than those in the control group,and the differences were statistically significant (P<0.05).Conclusion:Low-Dose dopamine is suitable for the treatment of elderly patients with chronic heart failure.It can significantly improve 24-hour urine output and heart rate,improve the treatment effect,shorten recovery time.

关键词

小剂量多巴胺/老年/慢性充血性心力衰竭/24h尿量/心率

Key words

Low-dose Dopamine/Elderly/Chronic congestive heart failure/24 h urine volume/Heart rate

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出版年

2024
中外医学研究
中国医院管理杂志社

中外医学研究

影响因子:1.149
ISSN:1674-6805
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