Effect of Peritoneal Dialysis Combined with Hemodialysis in the Treatment of End-stage Renal Disease
Objective:To study the effect of peritoneal dialysis combined with hemodialysis in the treatment of end-stage renal disease.Method:A total of 60 patients with end-stage renal disease admitted to Mianyang Central Hospital from June 2021 to December 2022.According to the random number table method,they were divided into a control group and an observation group,with 30 cases in each group.The control group received peritoneal dialysis treatment,while the observation group received hemodialysis treatment on the basis of the control group.The clinical efficacy,renal function indicators,inflammatory factors and immune indicators,and quality of life before and after treatment were compared of two groups.Result:The total effective rate of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).After treatment,the levels of serum creatinine(Scr),blood urea nitrogen(BUN),and 24-hour urinary protein in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).After treatment,the levels of high-sensitivity C-reactive protein(hs-CRP),procalcitonin(PCT),and CD8+in the observation group were lower than those in the control group,while CD4+was higher than that in the control group,the differences were statistically significant(P<0.05).After treatment,the observation group had higher scores in mental health,social function,general health,physiological function,energy,physical function,emotional function,and physiological function than the control group,and the differences were statistically significant(P<0.05).The incidence of complications in the observation group was lower than that in the control group,and the difference was statistically significant(χ2=11.429,P<0.05).Conclusion:Patients with end-stage renal disease can be treated with peritoneal dialysis combined with hemodialysis to improve their clinical outcomes and reduce the incidence of complications.
万方数据
维普
