Effect of Zishen Tiaomo Prescription Addition and Subtraction Combined with Acupuncture on Patients with Moderate and Severe IUA Kidney Deficiency and Blood Stasis Type after TCRA
Objective:To investigate the effect of Zishen Tiaomo Prescription addition and subtraction combined with acupuncture on patients with moderate and severe intrauterine adhesions(IUA)kidney deficiency and blood stasis type after transcervical resection of adhesion(TCRA).Method:A total of 82 patients with moderate and severe IUA after TCRA kidney deficiency and blood stasis type were selected from Guangzhou Panyu District Traditional Chinese Medicine Hospital from January 2022 to January 2024 as the study objects.According to a simple random method,they were divided into western medicine group(n=41)and Zishen Tiaomo group(n=41).The western medicine group was treated with conventional western medicine after operation,and the Zishen Tiaomo group was treated with Zishen Tiaomo Prescription addition and subtraction combined with acupuncture on the basis of western medicine group.Traditional Chinese medicine syndrome score,ultrasonic index,uterine adhesions condition before and after treatment,uterine morphology clinical efficacy,clinical efficacy,therapeutic effect and adverse reactions were compared between the two groups.Result:After treatment,the main disease,secondary disease scores and total scores of the two groups were decreased,and the main disease,secondary disease scores and total scores of the Zishen Tiaomo group were lower than those of the western medicine group,the differences were statistically significant(P<0.05).After treatment,endometrial thickness increased and resistance index(RI)and pulse index(PI)decreased in both groups,the endometrial thickness in Zishen Tiaomo group was higher than those in western medicine group,and RI and PI were lower than that in western medicine group,the differences were statistically significant(P<0.05).The total effective rate of uterine morphology was 90.24%in the Zishen Tiaomo group,which was significantly higher than 73.17%in the western medicine group,the difference was statistically significant(P<0.05).After treatment,the scores of intrauterine adhesions in both groups were decreased,and the scores of intrauterine adhesions in the Zishen Tiaomo group were lower than those in the western medicine group,the difference was statistically significant(P<0.05).The total effective rate of Zishen Tiaomo group was 90.24%,which was significantly higher than 70.73%of western medicine group,and the difference was statistically significant(P<0.05).During treatment,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Zishen Tiaomo Prescription addition and subtraction combined with acupuncture has a significant effect on patients with moderate and severe IUA kidney deficiency and blood stasis type after TCRA,which can reduce clinical symptoms,promote the return of uterine cavity shape to normal,improve uterine artery blood flow index,which is conducive to disease outcome and good safety.