Efficacy and Safety of FURL and PCNL in the Treatment of Kidney Stones with a Diameter of Less than 3 cm in Patients
Objective:To study the efficacy and safety of flexible ureteroscopic lithotripsy(FURL)and percutaneous nephrolithotomy(PCNL)in the treatment of kidney stones(KS)with a diameter of less than 3 cm in patients.Method:The clinical data of 90 patients with KS<3 cm diameter admitted to Youxi County General Hospital from June 2022 to December 2023 were retrospectively analyzed.According to different surgical methods,the patients were divided into study group and control group,45 cases in each group.The study group was treated with FURL and the control group was treated with PCNL.Perioperative indexes,complications,renal function indexes and inflammation indexes before and 48 h after surgery,and pain degree before and 24 h and 48 h after surgery were compared between the two groups.Result:The operation time and hospitalization time of the study group were shorter than those of the control group,and the amount of intraoperative blood loss was less than that of the control group,the differences were statistically significant(P<0.05).After operation,the incidence of complication of the study group was lower than that of the control group,the difference was statistically significant(P<0.05).At 48 h after operation,the levels of serum creatinine(Scr),blood urea nitrogen(BUN)and neutrophil gelatinase-associated lipid carrier protein(NGAL)in the study group were lower than those in the control group,the differences were statistically significant(P<0.05).At 48 h after operation,the levels of hypersensitive C-reactive protein(hs-CRP),interleukin-6(IL-6)and tumor necrosis factor-α(TNF-α)in the study group were lower than those in the control group,the differences were statistically significant(P<0.05).At 24 h after operation,visual analogue scale(VAS)score of the study group was lower than that of the control group,and the difference was statistically significant(P<0.05).Conclusion:The clinical effect of FURL and PCNL in the treatment of KS is exact,and there is no significant difference in the final stone clearance rate.Compared with PCNL,FURL has smaller intraoperative blood loss volume,shorter operation time,less influence on renal function,less inflammatory reaction in the body,and lower incidence of postoperative complications.FURL can be selected when KS patients meet the surgical indications.
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