首页|保妇康栓联合人干扰素α2a栓治疗子宫颈HPV感染的效果

保妇康栓联合人干扰素α2a栓治疗子宫颈HPV感染的效果

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目的:观察保妇康栓联合人干扰素α2a栓治疗子宫颈人乳头瘤病毒(human papillomavirus,HPV)感染的效果.方法:按照随机信封法对 2020 年 1 月—2024 年 1 月子长市人民医院收治的 80 例子宫颈HPV感染患者进行分组,对照组(40 例)采用人干扰素α2a栓治疗,研究组(40 例)采用保妇康栓联合人干扰素α2a栓,比较两组应用效果.结果:研究组治疗总有效率、HPV转阴率和CD3+、CD4+水平高于对照组,且中医症候积分和CD8+、肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)、白细胞介素-6(interleukin-6,IL-6)、C反应蛋白(C-reactive protein,CRP)水平低于对照组,临床症状消失时间短于对照组,差异有统计学意义(P<0.05),两组不良反应发生率比较,差异无统计学意义(P>0.05).结论:在人干扰素α2a栓治疗子宫颈HPV感染的基础上,保妇康栓的辅助使用能够进一步清除HPV感染,减轻子宫颈炎症刺激,改善局部环境免疫抵抗,缓解临床症状,治疗安全性和实用性较高.
The Effect of Baofukang Suppository Combined with Human Interferon α 2a Suppository in the Treatment of Cervical HPV Infection
Objective:To observe the effect of Baofukang Suppository combined with Human Interferon α2a Suppository in the treatment of cervical human papillomavirus(HPV)infection.Method:According to the random envelope method,80 cases of cervical HPV infection patients admitted to Zichang People's Hospital from January 2020 to January 2024 were divided into groups.The control group(40 cases)was treated with Human Interferon α2a Suppository,and the study group(40 cases)was treated with Bafukang Suppository combined with Human Interferon α2a Suppository.The application effect of the two groups was compared.Result:The total effective rate of treatment,the HPV conversion rate,CD3+and CD4+levels in the study group were higher than those in the control group,the traditional Chinese medicine syndrome score,CD8+,and tumor necrosis factor-α(TNF-α),interleukin-6(IL-6),and C-reactive protein(CRP)levels in the study group were lower than those in the control group,and the improvement time of clinical symptoms in the study group was shorter than that in the control group,the differences were statistically significant(P<0.05).There was no significant difference in the occurrence of adverse reactions between the two groups(P>0.05).Conclusion:On the basis of treating cervical HPV infection with Human Interferon α 2a Suppository,the auxiliary use of Baofukang Suppository can further eliminate HPV infection,reduce cervical inflammation stimulation,improve local environmental immune resistance,alleviate clinical symptoms,and have high treatment safety and practicality.

Baofukang SuppositoryHuman Interferon α 2a SuppositoryCervical HPV infection

贾琳、李晓琴

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子长市人民医院 陕西 子长 717300

保妇康栓 人干扰素α2a栓 子宫颈HPV感染

2024

中外医学研究
中国医院管理杂志社

中外医学研究

影响因子:1.149
ISSN:1674-6805
年,卷(期):2024.22(34)