Effect of Estradiol Drospirenone in the Treatment of Perimenopausal Syndrome Patients
Objective:To investigate the effect of Estradiol Drospirenone in the treatment of perimenopausal syndrome patients.Method:A total of 80 patients with perimenopausal syndrome admitted to Xiamen Haicang Hospital from May 2021 to April 2022 were selected as the study objects.They were divided into observation group and control group according to random number table method,with 40 cases in each group.The control group was given Tibolone Tablets and the observation group was given Estradiol Drospirodone Tablets.Symptom improvement time,osteoporosis index,sexual satisfaction and adverse reactions were compared between the two groups.Result:The improvement time of palpitations and chest tightness,headache and dizziness,insomnia,and anxiety in the observation group were significantly shorter than those in the control group,and the differences were statistically significant(P<0.05).The levels of alkaline phosphatase and bone calcitonin in observation group were higher than those in control group,and the differences were statistically significant(P<0.05).The female sexual quality indicator scale(FSFI)score and the proportion of sexual satisfaction in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).The incidence of adverse reactions in the observation group was significantly lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion:The use of Estradiol Drospirenone Tablets for women with perimenopausal syndrome can quickly alleviate clinical symptoms,improve osteoporosis,and enhance the quality of sexual life of patients,with few adverse reactions and high safety.
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