Analysis of Clinical Diagnostic Efficacy of EB Virus NA1-IgA Combined with VCA-IgA Detection on Patients with Nasopharyngeal Carcinoma
Objective:To analyze the clinical diagnostic efficacy of EB virus NA1-IgA combined with VCA-IgA detection on patients with nasopharyngeal carcinoma.Method:Blood samples of 783 patients undergoing nasopharyngeal carcinoma two items(EB virus NA1-IgA and VCA-IgA)routine were retrospectively analyzed from January 1,2021 to July 26,2023 in the inpatient and outpatient of Hechi People's Hospital.All samples were detected by EB virus NA1-IgA and VCA-IgA.The detection rate of nasopharyngeal carcinoma in NA1-IgA and VCA-IgA and its combined positive was compared.The diagnosis condition of nasopharyngeal carcinoma by NA1-IgA and VCA-IgA combination was analyzed.Result:Among the 783 patients,155 cases(19.80%)were NA1-IgA positive,114 cases(14.56%)were VCA-IgA positive,and 85 cases(10.86%)were both NA1-IgA and VCA-IgA positive.The detection rate of nasopharyngeal carcinoma in NA1-IgA and VCA-IgA positive patients was significantly higher than that in NA1-IgA and VCA-IgA alone positive patients,and the differences were statistically significant(P＜0.05).The sensitivity,specificity and accuracy of NA1-IgA combined with VCA-IgA in diagnosis of nasopharyngeal carcinoma were 98.67%(74/75),90.00%(9/10)and 97.65%(83/85)respectively.Conclusion:The combined detection of EB virus NA1-IgA and VCA-IgA has high clinical diagnostic efficacy in patients with nasopharyngeal carcinoma.
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