首页|床旁超声技术指导限制性液体复苏对创伤性休克患者的影响

床旁超声技术指导限制性液体复苏对创伤性休克患者的影响

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目的:探讨床旁超声技术指导限制性液体复苏(limited fluid resuscitation,LFR)对创伤性休克患者凝血功能的影响。方法:选择 2020 年 3 月—2023 年 3 月南通市通州区人民医院ICU收治的 66 例创伤性休克患者作为研究对象,根据随机数表法将 66 例患者分为观察组和对照组,各 33 例。对照组采用传统方法根据患者血压情况进行液体复苏治疗,观察组采用床旁超声技术指导LFR治疗。比较两组复苏前后血流动力学指标、凝血功能及预后指标。结果:两组复苏前后血流动力学指标比较,差异无统计学意义(P>0。05);复苏后,两组平均动脉压(mean arterial pressure,MAP)、中心静脉压(central venous pressure,CVP)高于复苏前,心率(heart rate,HR)低于复苏前,差异有统计学意义(P<0。05);观察组复苏液体总量少于对照组,差异有统计学意义(P<0。05)。复苏后,对照组凝血酶原时间(prothrombin time,PT)、活化部分凝血活酶时间(activated partial thromboplatin time,APTT)长于复苏前,纤维蛋白原(fibrinoger,FIB)、D二聚体(D-dimer,D-D)低于复苏前,观察组D-D低于复苏前,且观察组APTT、PT短于对照组,FIB高于对照组,D-D低于对照组,差异有统计学意义(P<0。05)。观察组ICU住院时间短于对照组,肺水肿发生率低于对照组,差异有统计学意义(P<0。05);两组 28 d病死率比较,差异无统计学意义(P>0。05)。结论:床旁超声技术指导创伤性休克患者进行LFR,可改善凝血功能,缩短ICU住院时间,降低肺水肿发生率,临床效果显著。
Effect of Bedside Ultrasound-guided Limited Fluid Resuscitation on Patients with Traumatic Shock
Objective:To explore the effect of bedside ultrasound-guided limited fluid resuscitation(LFR)on patients with traumatic shock.Method:A total of 66 patients with traumatic shock who admitted to ICU of Nantong Tongzhou People's Hospital from March 2020 to March 2023 were selected as the research objects,66 patients were divided into the observation group and the control group according to the random number table method,with 33 cases in each group.The control group was treated with liquid resuscitation according to the blood pressure of patients,and the observation group was treated with bedside ultrasound-guided LFR.The hemodynamic indexes,coagulation function before and after resuscitation and prognostic indexes were compared between two groups.Result:There were no significant differences in the hemodynamic indexes between two groups before and after resuscitation(P>0.05);after resuscitation,the mean arterial pressure(MAP)and central venous pressure(CVP)of two groups were higher than those before resuscitation,and the heart rate(HR)were lower than those before resuscitation,the differences were statistically significant(P<0.05);the total amount of resuscitation fluid in the observation group was less than that in the control group,and the difference was statistically significant(P<0.05).After resuscitation,the prothrombin time(PT)and activated partial thromboplastin time(APTT)of the control group were longer than before resuscitation,fibrinogen(FIB)and D-dimer(D-D)were lower than those before resuscitation,D-D in the observation group was lower than that before resuscitation,APTT and PT in the observation group were shorter than those in the control group,FIB was higher than that in the control group,and D-D was lower than that in the control group,the differences were statistically significant(P<0.05).The ICU hospitalization time of the observation group was shorter than that of the control group,and the incidence of pulmonary edema was lower than that of the control group,the differences were statistically significant(P<0.05);there was no significant difference in the 28 d mortality between two groups(P>0.05).Conclusion:Bedside ultrasound-guided LFR in patients with traumatic shock can improve coagulation function,shorten ICU hospitalization time,reduce the incidence of pulmonary edema,and the clinical effect is significant.

UltrasoundLimited fluid resuscitationTraumatic shockCoagulation function

倪浩亮

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南通市通州区人民医院 江苏 南通 226300

超声 限制性液体复苏 创伤性休克 凝血功能

2024

中外医学研究
中国医院管理杂志社

中外医学研究

影响因子:1.149
ISSN:1674-6805
年,卷(期):2024.22(35)