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高海拔静脉血栓栓塞症的研究进展

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静脉血栓栓塞症(VTE)是指血液在静脉内异常凝聚,阻塞管腔导致静脉回流。VTE可发生于全身静脉,主要包括深静脉血栓形成(DVT)和肺栓塞(PE)。VTE已成为继缺血性心脏病和脑卒中后的第三大心血管疾病死亡原因,并且是全球非传染性疾病的重大负担。随着海拔升高,气压降低,大气氧分压和肺泡氧分压也降低。高原环境血栓形成更为复杂,高原VTE的发病率显著增加。现将高海拔(HA)VTE发病机制及预防治疗措施进行综述。
Research Progress on High-altitude Venous Thromboembolism
Venous thromboembolism(VTE)refers to abnormal pooling of blood in the veins,blocking the lumen and causing venous backflow.VTE can occur in systemic veins,mainly including deep venous thrombosis(DVT)and pulmonary embolism(PE).VTE has become the third leading cause of cardiovascular death after ischemic heart disease and stroke,and represents a significant burden of non-communicable diseases globally.As the altitude increases,the air pressure decreases,and the atmospheric oxygen partial pressure and alveolar oxygen partial pressure also decrease.Thrombosis formation is more complex in high altitude environment,and the incidence of VTE at high altitude increases significantly.This article reviews the pathogenesis,prevention and treatment of high altitude(HA)VTE.

Venous thromboembolismHigh altitudeDeep venous thrombosisPulmonary embolism

史雪、詹睿、益西旺姆、尼珠、张云桃

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西藏大学医学院 西藏 拉萨 850000

拉萨市人民医院

静脉血栓栓塞症 高原 深静脉血栓 肺栓塞

2024

中外医学研究
中国医院管理杂志社

中外医学研究

影响因子:1.149
ISSN:1674-6805
年,卷(期):2024.22(35)