高海拔静脉血栓栓塞症的研究进展
Research Progress on High-altitude Venous Thromboembolism
史雪 1詹睿 1益西旺姆 2尼珠 2张云桃2
作者信息
- 1. 西藏大学医学院 西藏 拉萨 850000
- 2. 拉萨市人民医院
- 折叠
摘要
静脉血栓栓塞症(VTE)是指血液在静脉内异常凝聚,阻塞管腔导致静脉回流.VTE可发生于全身静脉,主要包括深静脉血栓形成(DVT)和肺栓塞(PE).VTE已成为继缺血性心脏病和脑卒中后的第三大心血管疾病死亡原因,并且是全球非传染性疾病的重大负担.随着海拔升高,气压降低,大气氧分压和肺泡氧分压也降低.高原环境血栓形成更为复杂,高原VTE的发病率显著增加.现将高海拔(HA)VTE发病机制及预防治疗措施进行综述.
Abstract
Venous thromboembolism(VTE)refers to abnormal pooling of blood in the veins,blocking the lumen and causing venous backflow.VTE can occur in systemic veins,mainly including deep venous thrombosis(DVT)and pulmonary embolism(PE).VTE has become the third leading cause of cardiovascular death after ischemic heart disease and stroke,and represents a significant burden of non-communicable diseases globally.As the altitude increases,the air pressure decreases,and the atmospheric oxygen partial pressure and alveolar oxygen partial pressure also decrease.Thrombosis formation is more complex in high altitude environment,and the incidence of VTE at high altitude increases significantly.This article reviews the pathogenesis,prevention and treatment of high altitude(HA)VTE.
关键词
静脉血栓栓塞症/高原/深静脉血栓/肺栓塞Key words
Venous thromboembolism/High altitude/Deep venous thrombosis/Pulmonary embolism引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据