首页|腹腔镜远端胃癌根治术后不同方式吻合对术后胃食管反流的影响观察

腹腔镜远端胃癌根治术后不同方式吻合对术后胃食管反流的影响观察

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目的:探究腹腔镜远端胃癌(GC)根治术后不同方式吻合对术后胃食管反流的影响。方法:选取 2018 年 1月—2023 年 10 月福建中医药大学附属第二人民医院收治的 80 例GC患者作为研究对象,所有患者均接受腹腔镜远端GC根治术治疗,根据术后吻合方式不同分成对照组(Billroth Ⅱ式+Braun吻合治疗,n=40)和研究组(非离断式Roux-en-Y治疗,n=40)。比较两组围手术期相关指标、胃食管反流情况、营养状态[血红蛋白(HB)、转铁蛋白(TRF)、清蛋白(ALB)、前清蛋白(PA)]和术后并发症的差异情况。结果:研究组手术时间、肛门排气时间、进食时间及住院时间等围手术期相关指标均低于对照组,差异有统计学意义(P<0。05);两组术后 5 d胃液pH水平显著高于术前,且研究组高于对照组,研究组术后GerdQ阳性、阴性症状评分均高于对照组,差异有统计学意义(P<0。05);两组的HB、TRF、ALB水平均高于术前,且研究组营养状态水平高于对照组,差异有统计学意义(P<0。05);两组的术后并发症发生率比较,差异无统计学意义(P>0。05);两组胃食管反流率比较,差异有统计学意义(P<0。05)。结论:针对GC患者,腹腔镜远端GC根治术后非离断式Roux-en-Y吻合效果显著,可减少手术创伤、促进术后恢复、减少胃酸反流、改善营养状态以及降低胃食管反流发生率。
Effects of Different Anastomosis on Gastroesophageal Reflux after Laparoscopic Distal Radical Gastrectomy
Objective:To explore the effects of different anastomosis on gastroesophageal reflux after laparoscopic distal radical gastrectomy.Method:80 patients with gastric cancer admitted to the Second People's Hospital Affiliated to Fujian University of Chinese Medicine from January 2018 to October 2023 were selected as the study objects.According to different anastomosis after laparoscopic distal radical gastrectomy,patients were divided into control group(Billroth Ⅱ+Braun anastomosis,n=40)and study group(non-disconnection Roux-en-Y,n=40).The perioperative indexes,gastroesophageal reflux,nutritional status[hemoglobin(HB),transferrin(TRF),albumin(ALB),prealbumin(PA)]and postoperative complications were compared between the two groups.Result:The operation time,anal exhaust time,eating time and length of hospital stay in study group were all lower than those in control group,and the difference was statistically significant(P<0.05).5 d after surgery,pH value of gastric fluid was significantly increased in both groups,and the study group was higher than control group,and the positive and negative symptoms scores of GerdQ in study group were higher than those in control group,and the difference was statistically significant(P<0.05).The levels of HB,TRF and ALB were increased in both groups,the study group was higher than control group,and the difference was statistically significant(P<0.05).There was no significant difference in the comparison of incidence of postoperative complications between the two groups(P>0.05).But there was significant difference in the comparsion of gastroesophageal reflux rate between the two groups(P<0.05).Conclusion:For patients with gastric cancer after laparoscopic distal radical gastrectomy,non-disconnection Roux-en-Y has significant anastomosis effect,which can reduce surgical trauma,promote postoperative recovery,reduce gastric acid reflux,improve nutritional status and reduce incidence of gastroesophageal reflux.

Gastric cancerLaparoscopeDistal radical gastrectomyAnastomosis modeGastroesophageal reflux

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福建中医药大学附属第二人民医院 福建 福州 350001

胃癌 腹腔镜 远端胃癌根治术 吻合方式 胃食管反流

2024

中外医学研究
中国医院管理杂志社

中外医学研究

影响因子:1.149
ISSN:1674-6805
年,卷(期):2024.22(36)