首页|经皮微创钢板内固定术在治疗胫骨骨折患者中的效果及对炎症因子的影响

经皮微创钢板内固定术在治疗胫骨骨折患者中的效果及对炎症因子的影响

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目的:探讨微创经皮钢板内固定治疗胫骨骨折的疗效及其对炎症因素的影响。方法:选取 2020 年 4 月—2023年 4 月龙岩市第二医院收治的 84 例胫骨骨折患者作为研究对象,根据不同手术方案分为对照组和微创组,每组各 42 例。对照组采用传统切开复位内固定术,微创组采用经皮微创钢板内固定术。比较两组围术期相关指标、术后炎症反应情况、术后疼痛应激相关指标情况、术后并发症情况及治疗效果优良率。结果:微创组围术期各项指标均优于对照组,差异有统计学意义(P<0。05);治疗后,微创组肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)及白细胞介素-8(IL-8)水平均低于对照组,差异有统计学意义(P<0。05);治疗后,微创组P物质(SP)、前列腺素E2(PGE 2)及神经肽(NPY)水平均低于对照组,差异有统计学意义(P<0。05);微创组术后并发症的总发生率低于对照组,差异有统计学意义(P<0。05);治疗后,微创组治疗优良率均高于对照组,差异有统计学意义(P<0。05)。结论:在胫骨骨折的治疗中,应用经皮微创钢板内固定具有良好的临床效果,能有效提高围手术期的各项指标,对炎症因子水平起到良好的控制作用,缓解术后疼痛,减少术后并发症的发生,有效提高治疗效果优良率。
Effect of Minimally Invasive Percutaneous Plate Fixation on Tibial Fractures and Its Effect on Inflammatory Factors
Objective:To investigate the effect of minimally invasive percutaneous plate internal fixation on tibial fracture and its effect on inflammatory factors.Method:Eighty-four patients with tibial fracture admitted to the Second Hospital of Longyan from April 2020 to April 2023 were selected as the study objects and divided into control group and minimally invasive group according to different surgical programs,with 42 cases in each group.Traditional open reduction internal fixation was performed in the control group,and percutaneous minimally invasive plate internal fixation was performed in the minimally invasive group.The perioperative relevant indexes,postoperative inflammatory response,postoperative pain stress related indexes,postoperative complications and the good and good rate of treatment effect were compared between the two groups.Result:The minimally invasive group perioperative indexes were better than those of control group(P<0.05).After treatment,levels of tumor necrosis factor-α(TNF-α),interleukin-6(IL-6)and interleukin-8(IL-8)of the minimally invasive group were lower than those of control group(P<0.05).The levels of substance P(SP),prostaglandin E2(PGE2)and Neuropeptide Y(NPY)of minimally invasive group were lower than those of control group(P<0.05).The minimally invasive group total incidence of postoperative complications was lower than that of the control group(P<0.05).After treatment,the excellent-effective rate in minimally invasive group was higher than that in control group(P<0.05).Conclusion:Minimally invasive percutaneous plate internal fixation for tibial fractures is ideal,which can effectively improve perioperative indicators.It plays a good control role in the level of inflammatory factors,and also canrelieve postoperative pain,reduce the occurrence of postoperative complications,and effectively improve the rate of excellent treatment effect.

Percutaneous minimally invasive plate internal fixationTibia fractureInflammatory factorsPain stress indexComplicationsExcellent-effective rate

黄魏翔、黄班华、马云杰、林万昌、游碧海

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龙岩市第二医院 福建 龙岩 364000

经皮微创钢板内固定术 胫骨骨折 炎症因子 疼痛应激指标 并发症 优良率

2024

中外医学研究
中国医院管理杂志社

中外医学研究

影响因子:1.149
ISSN:1674-6805
年,卷(期):2024.22(36)