Analysis of Macular Retinal Thickness Changes and Influencing Factors in Myopic Adolescents
Objective:To investigate the changes in macular retinal thickness in adolescents with myopia and analyze factors influencing these changes.Method:A total of 150 adolescent myopia patients admitted to Ophthalmology Department of Changzhou Wujin People's Hospital from May 2023 to March 2024 were selected as the study objects and divided into low,moderate,and high myopia groups according to Spherical Equivalent(SE),with 50 cases in each group.Additionally,50 individuals with normal vision were selected as the control group.General datas[gender,age,degree of refractive error,axial length(AL)and non-contact intraocular pressure(NCT)]of the four groups were compared.logistic linear regression analysis was used to identify factors causing changes in macular retinal thickness in the high myopia group and the normal vision group.Pearson correlation analysis method was used to test the association between 5 different parts of the macula(nasal side,upper side,lower side,temporal side,and overall retinal thickness)and AL and SE.Result:There were statistically significant differences in the comparison of degree of refractive error and AL among the four groups(P<0.05).logistic linear regression analysis showed that refractive error and axial length were the main factors influencing the variations in the macular retinal thickness.Pearson correlation analysis indicated that in the high myopia group,the retinal thickness on the nasal side and lower side was positively correlated with the degree of refractive error(r=0.408,0.332,P<0.05),whereas the overall macular retinal thickness was negatively correlated with the degree of refractive error(r=-0.285,P<0.05).The retinal thickness on the lower side,nasal side,and overall macula was negatively correlated with AL(r=-0.284,-0.333,-0.284,P<0.05).Conclusion:AL and degree of refractive error are significant factors causing an increase in macular retinal thickness in adolescents with myopia.Clinically,preventing the increase in AL and degree of refractive error is crucial for mitigating the progression of myopia in adolescents.
Adolescent myopiaMacular retinal thicknessPearson correlation analysisAxial lengthDegree of refractive error
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