中外医学研究2025,Vol.23Issue(22) :114-117.DOI:10.14033/j.cnki.cfmr.2025.22.030

佐匹克隆联合阿普唑仑对社区老年失眠症患者的影响

Impact of Zopiclone Combined with Alprazolam on Elderly Patients with Insomnia in the Community

张悦
中外医学研究2025,Vol.23Issue(22) :114-117.DOI:10.14033/j.cnki.cfmr.2025.22.030

佐匹克隆联合阿普唑仑对社区老年失眠症患者的影响

Impact of Zopiclone Combined with Alprazolam on Elderly Patients with Insomnia in the Community

张悦1
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作者信息

  • 1. 山东省慢性病医院 山东 青岛 266000
  • 折叠

摘要

目的:探讨佐匹克隆联合阿普唑仑对社区老年失眠症患者的临床效果.方法:选取 2023 年 9 月—2024 年 9 月山东省慢性病医院收治的 70 例老年失眠症患者作为研究对象,按照随机数表法将其分为对照组和观察组,每组各 35 例.对照组给予阿普唑仑治疗,观察组在此基础上增加佐匹克隆治疗.比较两组临床疗效、睡眠质量(PSQI)、认知功能(MMSE)及疗效满意度以及药物不良反应方面的差异.结果:治疗后,与对照组比较,观察组的PSQI评分、MMSE评分明显改善,观察组临床疗效及疗效满意度更高,差异有统计学意义(P<0.05).两组药物不良反应比较,差异无统计学意义(P>0.05).结论:佐匹克隆和阿普唑仑能有效提高老年失眠症患者的睡眠质量、认知功能和心理状态,提高疗效满意度.

Abstract

Objective:To investigate the clinical effect of Zopiclone and Alprazolam on elderly patients with insomnia in the community.Method:70 elderly insomnia patients treated in the Chronic Disease Hospital of Shandong Province from September 2023 to September 2024 were selected for this study.The patients were randomly assigned into control group receiving Alprazolam,and an observation group receiving both Alprazolam and Zopiclone,with 35 each group.Clinical efficacy,sleep quality(PSQI),cognitive function(MMSE),treatment satisfaction,and adverse drug reactions between the two groups were compared.Result:After treatment,the observation group showed significant improvements in PSQI and MMSE scores compared to the control group.The clinical efficacy and treatment satisfaction were also significantly higher in the observation group,with statistically significant differences(P<0.05).There was no statistically significant difference in adverse drug reactions between the two groups(P>0.05).Conclusion:The combination of Zopiclone and Alprazolam effectively improves sleep quality,cognitive function,and psychological status in elderly insomnia patients,and enhances treatment satisfaction.

关键词

佐匹克隆/阿普唑仑/老年失眠症/睡眠质量

Key words

Zopiclone/Alprazolam/Elderly insomnia/Sleep quality

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出版年

2025
中外医学研究
中国医院管理杂志社

中外医学研究

影响因子:1.149
ISSN:1674-6805
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