Correlation between the severity of nonalcoholic fatty liver disease and carotid atherosclerosis and intima-media thickness and risk factor analysis
Objective:To investigate the correlation between the severity of nonalcoholic fatty liver disease(NAFLD)and carotid plaque and carotid intima-media thickness(cIMT),and analyze the risk factors.Methods:A total of 154 patients who underwent liver and carotid ultrasound examination and were diagnosed with NAFLD from January to November 2021 were collected.The severity of NAFLD,carotid plaque and vascular stenosis were evaluated to measure the cIMT value of the patients,and the liver fibrosis score was calculated,and the statistical analysis was performed.Results:The cIMT and incidence of stenosis were lower in the mild NAFLD group than in the moderate-severe group,and the differences were statistically significant(W =6 905.500,P＜0.001).cIMT values were significantly higher in the group with carotid atherosclerotic plaque than in the group without carotid atherosclerotic plaque,and the differences were statistically significant(W =3 361.500,P＜0.001).BMI was an independent risk factor for NAFLD severity and cIMT,age and NAFLD severity were an independent risk factor for cIMT.Age,hypertension,and liver fibrosis score were independent risk factors for carotid atherosclerotic plaque,with statistically significant differences(P＜0.05).Conclusion:The increase of cIMT and carotid stenosis are related to the severity of NAFLD,and the incidence of carotid plaque is positively correlated with cIMT.In addition,increasing liver fibrosis score was indicative of the presence of carotid atherosclerotic plaque.
NETL
NSTL
万方数据
维普
