Meta-analysis of risk factors of malnutrition in patients with liver cancer
Objective:To systematically review the risk factors of malnutrition in patients with liver cancer.Methods:A computer-based search of Chinese and English databases was conducted to identify Case-control study related literature on risk factors of malnutrition in patients with liver cancer,to provide a reference for the prevention and treatment of malnutrition in patients with liver cancer.The time frame of the search was from the establishment of the database to April 2022,the quality of the literature was evaluated and the data were analyzed by RevMan 5.4 software.Results:A total of 2 353 patients were included in 13 articles,including one in English and 12 in Chinese.The Meta-analysis shows that:Age,BMI,TNM,Child-pugh,Anemia,Alb,PA(P>0.05).It is a risk factor for malnutrition in patients with liver cancer,sex,marital status,hepatitis B,alanine transaminase,aspartate transaminase,etc.There was no significant statistical significance(P>0.05).Conclusion:There are many risk factors of malnutrition in patients with liver cancer,age,BMI,TNM,child-pugh,anemia,ALB,and PA were the main risk factors for malnutrition.