首页|健脾疏肝散结方联合腹针对代谢相关脂肪性肝病患者肝功能和血脂等的影响

健脾疏肝散结方联合腹针对代谢相关脂肪性肝病患者肝功能和血脂等的影响

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目的:探讨健脾疏肝散结方联合腹针治疗代谢相关脂肪性肝病的效果及对患者肝功能和血脂的影响.方法:选择2021 年1 月至2022 年7 月接受治疗的代谢相关脂肪性肝病患者100 例作为研究对象,按照随机数字表法将患者分为对照组与观察组各50 例.对照组患者实施常规西医治疗,观察组患者在常规西医治疗基础上采取健脾疏肝散结方联合腹针治疗,比较两组患者的总有效率、血脂指标、肝功能指标、睡眠状况指标、生活质量评分.结果:观察组、对照组总有效率分别为 98.00%、86.00%,观察组高于对照组(P<0.05).与治疗前相比,两组患者治疗后TC、TG、LDL-C均降低(P<0.05),两组患者治疗后HDL-C均增高(P<0.05);治疗后,观察组患者的TC、TG、LDL-C均低于对照组(P<0.05),HDL-C高于对照组(P<0.05).与治疗前相比,两组患者的血清AST、ALT、TBA、TBil水平均在治疗后降低(P<0.05);治疗后,观察组的血清 AST、ALT、TBA、TBil水平均低于对照组(P<0.05).与治疗前相比,两组患者的入睡潜伏期在治疗后均降低(P<0.05),治疗后的实际睡眠时长均延长(P<0.05),治疗后的PSQI评分均降低(P<0.05);治疗后,观察组的入睡潜伏期较对照组更短(P<0.05),实际睡眠时长较对照组更长(P<0.05),PSQI评分较对照组更低(P<0.05).与治疗前相比,两组患者的生活质量各因子评分均在治疗后增高(P<0.05);治疗后,观察组的生活质量各因子评分均较对照组更高(P<0.05).结论:健脾疏肝散结方联合腹针治疗可调节代谢相关脂肪性肝病患者的血脂水平,改善其肝功能,具有良好的疗效,有利于改善患者睡眠及生活质量.
Effect of Jianpi Shugan Sanjie Decoction combined with abdominal acupuncture on Metabolic-dysfunction-associatedfatty liver disease and influence on liver function and blood lipid index
Objective:To explore the effect of Jianpi Shugan Sanjie Decoction combined with abdominal acupuncture on metabolic dysfunction-associated fatty liver disease(MAFLD)and its influence on liver function and blood lipid indexes of patients.Methods:100 cases of patients with MAFLD from January 2021 to July 2022 were selected as the research object,and randomly divided into the control group and the observation group with 50 cases in each group according to the random number table method.The control group was treated with conventional western medicine,while the observation group was treated with Jianpi Shugan Sanjie Recipe combined with abdominal acupuncture on the basis of conventional western medicine.The total effective rate,blood lipid index,liver function index,sleep status index and quality of life score were compared between the two groups.Results:The total effective rates of the observation group and the control group were 98.00%and 86.00%respectively,and the observation group was higher than the control group(P<0.05).Compared with before treatment,TC,TG and LDL-C in both groups decreased after treatment(P<0.05),while HDL-C in both groups increased after treatment(P<0.05).After treatment,TC,TG and LDL-C in the observation group were lower than those in the control group(P<0.05),while HDL-C in the observation group was higher than that in the control group(P<0.05).Compared with before treatment,the levels of serum AST,ALT,TBA and TBil in both groups decreased after treatment(P<0.05).After treatment,the levels of serum AST,ALT,TBA and TBIL in the observation group were lower than those in the control group(P<0.05).Compared with before treatment,the sleep latency of both groups decreased after treatment(P<0.05),the actual sleep duration of both groups prolonged after treatment(P<0.05),and the PSQI scores of both groups decreased after treatment(P<0.05).After treatment,the sleep latency of the observation group was shorter than that of the control group(P<0.05),the actual sleep duration of the observation group was longer than that of the control group(P<0.05),and the PSQI score of the observation group was lower than that of the control group(P<0.05).Compared with before treatment,the scores of all factors of quality of life in both groups increased after treatment(P<0.05).After treatment,the scores of all factors of quality of life in the observation group were higher than those in the control group(P<0.05).Conclusion:Jianpi Shugan Sanjie Recipe combined with abdominal acupuncture can regulate the blood lipid level and improve the liver function of MAFLD patients,which has good curative effect and is beneficial to improve the sleep and quality of life of patients.

metabolic dysfunction-associated fatty liver diseaseShugan Jianpi Sanjie recipeabdominal acupuncture

韩立娟、孙凤霞、齐建永、王珊珊、孙华新、任金花、宗瑞强、徐伟

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河北省唐山市丰润区中医院肝胆脾胃科 (河北 唐山,064000)

北京市中医院肝病科

唐山市丰润区人民医院消化内科

代谢相关脂肪性肝病 健脾疏肝散结方 腹针

河北省高层次人才项目中国肝炎防治基金会中西医结合肝病项目

C20221118YGFK20210026

2024

中西医结合肝病杂志
中国中西医结合学会,湖北中医学院

中西医结合肝病杂志

CSTPCD
影响因子:0.908
ISSN:1005-0264
年,卷(期):2024.34(4)
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